Intrapulmonary arteriovenous anastomoses in humans–response to exercise and the environment

AT Lovering, JW Duke, JE Elliott - The Journal of physiology, 2015 - Wiley Online Library
Intrapulmonary arteriovenous anastomoses (IPAVA) have been known to exist in human
lungs for over 60 years. The majority of the work in this area has largely focused on …

Increased cardiac output, not pulmonary artery systolic pressure, increases intrapulmonary shunt in healthy humans breathing room air and 40% O2

JE Elliott, JW Duke, JA Hawn, JR Halliwill… - The Journal of …, 2014 - Wiley Online Library
Key points The contribution of blood flow through intrapulmonary arteriovenous
anastomoses (IPAVAs) to pulmonary gas exchange efficiency remains unknown and …

Cardiopulmonary haemodynamics in Tibetans and Han Chinese during rest and exercise

FN Möller, JL Fan, JE Futral… - The Journal of …, 2024 - Wiley Online Library
During sea‐level exercise, blood flow through intrapulmonary arteriovenous anastomoses
(IPAVA) in humans without a patent foramen ovale (PFO) is negatively correlated with …

Clinical consideration for techniques to detect and quantify blood flow through intrapulmonary arteriovenous anastomoses: lessons from physiological studies

JW Duke, JE Elliott, AT Lovering - Echocardiography, 2015 - Wiley Online Library
Intrapulmonary arteriovenous anastomoses (IPAVA) are large diameter (> 50 μm) vascular
conduits, present in> 95% of healthy humans. Because IPAVA are large diameter pathways …

AltitudeOmics: impaired pulmonary gas exchange efficiency and blunted ventilatory acclimatization in humans with patent foramen ovale after 16 days at 5,260 m

JE Elliott, SS Laurie, JP Kern… - Journal of Applied …, 2015 - journals.physiology.org
A patent foramen ovale (PFO), present in∼ 40% of the general population, is a potential
source of right-to-left shunt that can impair pulmonary gas exchange efficiency [ie, increase …

Decreased arterial , not O2 content, increases blood flow through intrapulmonary arteriovenous anastomoses at rest

JW Duke, JT Davis, BJ Ryan, JE Elliott… - The Journal of …, 2016 - Wiley Online Library
Key points The mechanism (s) that regulate hypoxia‐induced blood flow through
intrapulmonary arteriovenous anastomoses (QIPAVA) are currently unknown. Our previous …

Hypoxia, not pulmonary vascular pressure, induces blood flow through intrapulmonary arteriovenous anastomoses

JC Tremblay, AT Lovering, PN Ainslie… - The Journal of …, 2015 - Wiley Online Library
Key points Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is
increased by acute hypoxia during rest by unknown mechanisms. Oral administration of …

Impaired pulmonary gas exchange efficiency, but normal pulmonary artery pressure increases, with hypoxia in men and women with a patent foramen ovale

JW Duke, KM Beasley, JP Speros… - Experimental …, 2020 - Wiley Online Library
New Findings What is the central question of this study? Do individuals with a patent
foramen ovale (PFO+) have a larger alveolar‐to‐arterial difference in () than those without …

Pulmonary arterial response to Angiostrongylus vasorum in naturally infected dogs: echocardiographic findings in two cases

A Corda, S Carta, A Varcasia, C Tamponi… - Parasites & vectors, 2019 - Springer
Background Angiostrongylus vasorum is a nematode living in the pulmonary arteries of
canids. Infected dogs develop severe pulmonary lesions which can potentially lead to …

Evaluation of intrapulmonary arteriovenous anastomoses before and after oxygen supplementation, using transthoracic agitated saline contrast echocardiography in …

C Lee, M Kim, JI Han, K Lee, H Yoon - Frontiers in Veterinary Science, 2024 - frontiersin.org
Introduction Intrapulmonary arteriovenous anastomoses (IPAVAs) are defined as relatively
large, dynamic shunt vessels that connect the pulmonary arterial and venous systems …