Clinical implications of sperm DNA damage in IVF and ICSI: updated systematic review and meta‐analysis

J Ribas‐Maynou, M Yeste, N Becerra‐Tomás… - Biological …, 2021 - Wiley Online Library
The clinical effect of sperm DNA damage in assisted reproduction has been a controversial
topic during recent decades, leading to a variety of clinical practice recommendations. While …

Mitochondria: their role in spermatozoa and in male infertility

M Boguenet, PE Bouet, A Spiers… - Human …, 2021 - academic.oup.com
BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

[HTML][HTML] Sperm lipid markers of male fertility in mammals

S Shan, F Xu, M Hirschfeld, B Brenig - International Journal of Molecular …, 2021 - mdpi.com
Sperm plasma membrane lipids are essential for the function and integrity of mammalian
spermatozoa. Various lipid types are involved in each key step within the fertilization …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

[HTML][HTML] A systematic review identifying fertility biomarkers in semen: A clinical approach through Omics to diagnose male infertility

M Llavanera, A Delgado-Bermudez, J Ribas-Maynou… - Fertility and …, 2022 - Elsevier
Objective To identify the most robust molecular biomarkers in sperm and seminal plasma for
the diagnosis of male infertility, and to evaluate their clinical use. Design Systematic review …

[HTML][HTML] Mechanisms of ROS-induced mitochondria-dependent apoptosis underlying liquid storage of goat spermatozoa

T Liu, Y Han, T Zhou, R Zhang, H Chen, S Chen… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Liquid storage of spermatozoa is important for artificial insemination and herd genetic
breeding. However, the extended time of storage inducing the rapid decline in spermatozoa …

[HTML][HTML] Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization

CM Rival, W Xu, LS Shankman, S Morioka… - Nature …, 2019 - nature.com
Fertilization is essential for species survival. Although Izumo1 and Juno are critical for initial
interaction between gametes, additional molecules necessary for sperm: egg fusion on both …

Associations of urinary trichloroacetic acid concentrations with spermatozoa apoptosis and DNA damage in a Chinese population

YJ Chen, C Liu, ZZ Tu, Q Lu, C Messerlian… - Environmental …, 2022 - ACS Publications
Exposure to trichloroacetic acid (TCAA) has been associated with impaired semen quality;
however, its association with spermatozoa apoptosis and DNA damage remains unclear …

Teratozoospermia: Its association with sperm DNA defects, apoptotic alterations, and oxidative stress

O Ammar, M Mehdi, M Muratori - Andrology, 2020 - Wiley Online Library
This study was carried out to evaluate the level of nuclear sperm DNA damage in men with
isolated polymorphic teratozoospermia and examining its relationship with apoptosis and …

Increased sperm DNA fragmentation in infertile men with varicocele: relationship with apoptosis, seminal oxidative stress, and spermatic parameters

O Ammar, O Tekeya, I Hannachi, A Sallem… - Reproductive …, 2021 - Springer
This study intends to determine the extent of nuclear sperm injury in patients with varicocele
and to investigate its relationship with apoptosis and oxidative stress (OS). Ejaculated sperm …