[HTML][HTML] Drug efflux pump inhibitors: a promising approach to counter multidrug resistance in Gram-negative pathogens by targeting AcrB protein from AcrAB-TolC …
R Alenazy - Biology, 2022 - mdpi.com
Simple Summary Multidrug-resistant bacterial infections, especially that caused by Gram-
negative bacteria, have posed serious health issues worldwide. Bacteria have different …
negative bacteria, have posed serious health issues worldwide. Bacteria have different …
Emerging Transcriptional and Genomic Mechanisms Mediating Carbapenem and Polymyxin Resistance in Enterobacteriaceae: a Systematic Review of Current …
The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …
[HTML][HTML] Relationship between Biofilm-Formation, Phenotypic Virulence Factors and Antibiotic Resistance in Environmental Pseudomonas aeruginosa
The formation of a protective biofilm by Pseudomonas aeruginosa (PA) is one of the
hallmarks of their survival both in vivo and in harsh environmental conditions, thus, biofilm …
hallmarks of their survival both in vivo and in harsh environmental conditions, thus, biofilm …
[HTML][HTML] The culmination of multidrug-resistant efflux pumps vs. meager antibiotic arsenal era: Urgent need for an improved new generation of EPIs
S Chetri - Frontiers in Microbiology, 2023 - frontiersin.org
Efflux pumps function as an advanced defense system against antimicrobials by reducing
the concentration of drugs inside the bacteria and extruding the substances outside. Various …
the concentration of drugs inside the bacteria and extruding the substances outside. Various …
The development of efflux pump inhibitors to treat Gram-negative infections
P Blanco, F Sanz-García… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: One of the possibilities for reducing the emergence and spread of antibiotic
resistance is the use of anti-resistance compounds capable of resensitizing resistant …
resistance is the use of anti-resistance compounds capable of resensitizing resistant …
[HTML][HTML] Characterisation of Non-Carbapenemase-Producing Carbapenem-Resistant Klebsiella pneumoniae Based on Their Clinical and Molecular Profile in …
YQ Lee, S Sri La Sri Ponnampalavanar, CW Chong… - Antibiotics, 2022 - mdpi.com
Non-carbapenemase-producing carbapenem-resistant Klebsiella pneumoniae (NC-CRKP)
confers carbapenem resistance through a combination of chromosomal mutations and …
confers carbapenem resistance through a combination of chromosomal mutations and …
Bacterial effluxome as a barrier against antimicrobial agents: structural biology aspects and drug targeting
P Brindangnanam, AR Sawant, K Prashanth… - Tissue …, 2022 - Taylor & Francis
Antimicrobial resistance (AMR) is fast becoming a medical crisis affecting the entire global
population. The bacterial membrane is the first layer of defense for the bacteria against …
population. The bacterial membrane is the first layer of defense for the bacteria against …
Exploring imidazo[4,5-g]quinoline-4,9-dione derivatives as Acinetobacter baumannii efflux pump inhibitor: an in silico approach
P Brindangnanam, K Ashokkumar… - Journal of …, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) is fast becoming a medical crisis affecting the entire global
population. World Health Organization (WHO) statistics show that globally 0.7 million people …
population. World Health Organization (WHO) statistics show that globally 0.7 million people …
Evaluation of chromosomally and acquired mechanisms of resistance to carbapenem antibiotics among clinical isolates of Pseudomonas aeruginosa in Kerman, Iran
Z Hashemizadeh, S Mansouri, F Pahlavanzadeh… - Gene Reports, 2020 - Elsevier
Introduction Multidrug-resistant (MDR) of Pseudomonas aeruginosa isolates are increasing
around the world which can cause serious problems for antimicrobial therapy in hospital …
around the world which can cause serious problems for antimicrobial therapy in hospital …
[PDF][PDF] 北京与银川两家医院耐碳青霉烯类肠杆菌科细菌的流行特征研究
徐旋， 李刚， 贾天野， 张敬霞， 陈素明， 张树永， 贾伟… - 中国抗生素杂志, 2020 - zgkss.com.cn
目的调查研究北京与银川两家医院耐碳青霉烯类肠杆菌(carbapenem-resistance
Enterobacteriaceae, CRE) 的流行病学特征, 为CRE 的临床诊治及其传播控制提供依据 …
Enterobacteriaceae, CRE) 的流行病学特征, 为CRE 的临床诊治及其传播控制提供依据 …