For more than 20 years, moderately raised concentrations of total homocysteine (tHcy) have
been associated with an increased risk of atherothrombotic vascular events but only recently …

Purpose: To review epidemiologic studies on the association between homocyst (e) ine
level and risk for cardiovascular disease and the potential benefits of homocysteine …

Inflammation plays a major role in atherothrombosis, and measurement of inflammatory
markers such as high-sensitivity C-reactive protein (HSCRP) may provide a novel method …

Context.—Hyperhomocysteinemia is caused by genetic and lifestyle influences, including
low intakes of folate and vitamin B6. However, prospective data relating intake of these …

OBJECTIVE To determine whether an elevated homocysteine level is an independent risk
factor for the development of coronary heart disease (CHD) to aid the US Preventive …

Background—Sudden cardiac death (SCD) is an important cause of mortality even among
apparently healthy populations. However, our ability to identify those at risk for SCD in the …

Background A recent review of epidemiologic literature found consistently reduced cancer
and heart disease rates in persons with high compared with low whole-grain intakes …

On the basis of recent retrospective and prospective studies, it is now widely accepted that
increased total plasma homocysteine is a risk factor for cardiovascular disease. Impaired …

High plasma levels of homocysteine are the results of the interplay between congenital and
environmental factors. In the last two decades, a growing amount of interest has focused on …

Background—Elevated plasma total homocysteine (tHcy), low B-vitamin intake, and genetic
polymorphisms related to tHcy metabolism may play roles in coronary heart disease (CHD) …