Candida albicans Biofilms and Human Disease

CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

Candida glabrata: a review of its features and resistance

CF Rodrigues, S Silva, M Henriques - European journal of clinical …, 2014 - Springer
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and
vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous …

[HTML][HTML] Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes

T Schwarzmueller, B Ma, E Hiller, F Istel… - PLoS …, 2014 - journals.plos.org
The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis,
causing infections ranging from superficial to life-threatening disseminated disease. The …

Candida albicans biofilms: building a heterogeneous, drug-tolerant environment

J Bonhomme, C d'Enfert - Current opinion in microbiology, 2013 - Elsevier
Highlights•We discuss recent advances in understanding fungal biofilm
development.•Fungal biofilm formation is under the control of complex transcriptional …

Candida albicans Biofilm Development and Its Genetic Control

JV Desai, AP Mitchell - Microbial Biofilms, 2015 - Wiley Online Library
The human commensal Candida albicans is the leading fungal colonizer of implanted
medical devices and a frequent cause of nosocomial infections (1, 2). Several Candida …

[HTML][HTML] Cigarette smoke condensate increases C. albicans adhesion, growth, biofilm formation, and EAP1, HWP1 and SAP2 gene expression

A Semlali, K Killer, H Alanazi, W Chmielewski… - BMC microbiology, 2014 - Springer
Background Smokers are more prone to oral infections than are non-smokers. Cigarette
smoke reaches the host cells but also microorganisms present in the oral cavity. The contact …

[HTML][HTML] DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

DA Magditch, TB Liu, C Xue, A Idnurm - 2012 - journals.plos.org
The disease cryptococcosis, caused by the fungus Cryptococcus neoformans, is acquired
directly from environmental exposure rather than transmitted person-to-person. One …

[HTML][HTML] The Candida albicans ENO1 gene encodes a transglutaminase involved in growth, cell division, morphogenesis, and osmotic protection

E Reyna-Beltrán, M Iranzo… - Journal of Biological …, 2018 - ASBMB
Candida albicans is an opportunistic fungus that is part of the normal microflora commonly
found in the human digestive tract and the normal mucosa or skin of healthy individuals …

[HTML][HTML] Hypoxia and Temperature Regulated Morphogenesis in Candida albicans

PR Desai, L van Wijlick, D Kurtz, M Juchimiuk… - PLoS …, 2015 - journals.plos.org
Candida albicans is a common commensal in the human gut but in predisposed patients it
can become an important human fungal pathogen. As a commensal, C. albicans adapts to …

Identification of genes upregulated by the transcription factor Bcr1 that are involved in impermeability, impenetrability, and drug resistance of Candida albicans a/α …

T Srikantha, KJ Daniels, C Pujol, E Kim, DR Soll - Eukaryotic cell, 2013 - Am Soc Microbiol
Candida albicans forms two types of biofilm, depending upon the configuration of the mating
type locus. Although architecturally similar, a/α biofilms are impermeable, impenetrable, and …