Vetinformatics from functional genomics to drug discovery: insights into decoding complex molecular mechanisms of livestock systems in veterinary science

RK Pathak, JM Kim - Frontiers in Veterinary Science, 2022 - frontiersin.org
Having played important roles in human growth and development, livestock animals are
regarded as integral parts of society. However, industrialization has depleted natural …

Genomic identification, evolution and sequence analysis of the heat-shock protein gene family in buffalo

SU Rehman, A Nadeem, M Javed, F Hassan, X Luo… - Genes, 2020 - mdpi.com
Heat-shock proteins (HSP) are conserved chaperones crucial for protein degradation,
maturation, and refolding. These adenosine triphosphate dependent chaperones were …

Genome-wide analysis of genetic diversity and selection signatures in three Indian sheep breeds

KA Saravanan, M Panigrahi, H Kumar, B Bhushan… - Livestock Science, 2021 - Elsevier
Abstract Knowledge about genetic diversity and selection signatures are very essential for
the management and sustainable utilization of sheep genetic resources in India. In this …

[HTML][HTML] Genome-Wide Analysis of Heat Shock Protein Family and Identification of Their Functions in Rice Quality and Yield

H Wang, S Charagh, N Dong, F Lu, Y Wang… - International Journal of …, 2024 - mdpi.com
Heat shock proteins (Hsps), acting as molecular chaperones, play a pivotal role in plant
responses to environmental stress. In this study, we found a total of 192 genes encoding …

Identification of potential candidate vaccines against Mycobacterium ulcerans based on the major facilitator superfamily transporter protein

TZ Ishwarlall, VT Adeleke, L Maharaj… - Frontiers in …, 2022 - frontiersin.org
Buruli ulcer is a neglected tropical disease that is characterized by non-fatal lesion
development. The causative agent is Mycobacterium ulcerans (M. ulcerans). There are no …

Genome-wide association study of trypanosome prevalence and morphometric traits in purebred and crossbred Baoulé cattle of Burkina Faso

B Yougbaré, A Soudré, D Ouédraogo, BL Zoma… - PloS one, 2021 - journals.plos.org
In this study, single-SNP GWAS analyses were conducted to find regions affecting tolerance
against trypanosomosis and morphometrics traits in purebred and crossbred Baoulé cattle of …

Genetic polymorphism in HSPB6 gene and their association with heat tolerance traits in Indian Karan Fries (Bos taurus x Bos indicus) cattle

R Kumar, ID Gupta, A Verma, S Singh… - Animal …, 2022 - Taylor & Francis
Heat shock proteins (HSPs) act as a chaperone activity ensuring the folding, unfolding, and
refolding of denatured proteins, which help in a protective role during thermal stress in dairy …

Novel single nucleotide polymorphisms in the heat shock protein 70.1 gene in South African Nguni crossbred cattle

LS Mkize, OT Zishiri - Tropical animal health and production, 2020 - Springer
High environmental temperatures are one of the main causes of reduced productivity and
reproduction in livestock. In an endeavour to counteract the effects of high temperature, a …

[HTML][HTML] Evaluation of quality and gene expression of goat embryos produced in vivo and in vitro after cryopreservation

JC Ferreira-Silva, RLO Silva, JIT Vieira, JB Silva… - Cryobiology, 2021 - Elsevier
In the present study, we aimed to identify morphological and molecular changes of in vivo
and in vitro-produced goat embryos submitted to cryopreservation. In vivo embryos were …

Vet informatics and the future of drug discovery in veterinary medicine

MC Vlasiou - Frontiers in Veterinary Science, 2024 - frontiersin.org
Vet informatics-the application of data analytics, bioinformatics, and computational tools to
manage and analyze biological and clinical data in veterinary science-is revolutionizing …