Beyond cytotoxic potency: disposition features required to design ADC payload
H Sun, LC Wienkers, A Lee - Xenobiotica, 2024 - Taylor & Francis
Antibody-drug conjugates (ADCs) have demonstrated impressive clinical usefulness in
treating several types of cancer, with the notion of widening of the therapeutic index of the …
treating several types of cancer, with the notion of widening of the therapeutic index of the …
An efficient lung cancer detection using optimal SVM and improved weight based beetle swarm optimization
N Venkatesan, S Pasupathy, B Gobinathan - Biomedical Signal Processing …, 2024 - Elsevier
Lung cancer is caused by uncontrolled cell growth in the lung tissue. Early detection of lung
cancer is important for correct detection and availability of treatment. Diagnosing lung …
cancer is important for correct detection and availability of treatment. Diagnosing lung …
Targeting urotensin II with silymarin: potential therapeutic strategies for diabetes and associated cardiovascular complications
S Sabarathinam - Phytochemistry Reviews, 2024 - Springer
Diabetes and its associated comorbidities have garnered significant attention in recent
decades, leading to continuous exploration of diagnostic and treatment options. Urotensin II …
decades, leading to continuous exploration of diagnostic and treatment options. Urotensin II …
[HTML][HTML] Aniline Derivatives Containing 1-Substituted 1, 2, 3-Triazole System as Potential Drug Candidates: Pharmacokinetic Profile Prediction, Lipophilicity Analysis …
E Chrobak, K Bober-Majnusz, M Wyszomirski, A Zięba - Pharmaceuticals, 2024 - mdpi.com
Background: The triazole ring is an attractive structural unit in medicinal chemistry, and
chemical compounds containing this type of system in their structure exhibit a wide spectrum …
chemical compounds containing this type of system in their structure exhibit a wide spectrum …
Synthesis, Anticancer Activity, and Computational Studies of New Pyrazole Derivatives
AE Khairulah, ZA Shuhaib, RA Alharis… - Russian Journal of …, 2024 - Springer
Abstract new pyrazole derivatives were synthesized through a cyclization reaction of
chalcones derivatives with hydrazine hydrate under acidic catalysis and characterization by …
chalcones derivatives with hydrazine hydrate under acidic catalysis and characterization by …
Sesquiterpene Lactones as Potential G1/S Phase Cell Cycle Inhibitors: A Molecular Docking Study: Sesquiterpene Lactones as Potential Cell Cycle Inhibitors
Cell cycle checkpoints play a crucial role in cell division by monitoring the orderly
progression of each phase, ensuring accurate completion before advancing to the next …
progression of each phase, ensuring accurate completion before advancing to the next …
Molecular Docking-Aided Identification of Natural Bioactive Molecules as Potential Cancer Cell Proliferation Inhibitors: Molecular Docking as Cancer Cell Inhibitors
I Hassan, A Zaman, E Zafar, M Khan - Futuristic Biotechnology, 2024 - fbtjournal.com
Cancer is the second leading cause of death worldwide. Uncontrolled proliferation of cells is
a hallmark of cancer development and progression. Ki-67 (a marker of proliferation Kiel-67) …
a hallmark of cancer development and progression. Ki-67 (a marker of proliferation Kiel-67) …
Identification of Lung Cancer Using Particle Swarm Optimization and Machine Learning Technique
Lung cancer is a specific kind of malignancy that arises in the tissues of the lungs,
specifically in the cells that comprise the lining of the respiratory passages. Smoking is well …
specifically in the cells that comprise the lining of the respiratory passages. Smoking is well …