Trypanosomes and leishmania, the causative agents of several tropical diseases, possess a
unique redox metabolism which is based on trypanothione. The bis (glutathionyl) …

The protozoan hemoflagellates belonging to the order Kinetoplastida, which comprise the
genera Trypanosoma and Leishmania, are the causative agents of a number of important …

Peroxisomes of organisms belonging to the protist group Kinetoplastea, which include
trypanosomatid parasites of the genera Trypanosoma and Leishmania, are unique in …

Mala'c dchydrogcna,, cs hch} ng to lhc most active enzyme', m glyt, xysomcs, mitochondria,
pcroxisomcs, chloroplasts and the eylosol. In this revicv,, the prop,. riles and the role of the …

The trypanosomatid metabolite N1, N8-bis-(glutathionyl) spermidine (trypanothione) has
been demonstrated to form a stable adduct with the aromatic arsenical drug melarsen oxide …

In trypanosomes the first part of glycolysis takes place in specialized microbodies, the
glycosomes. Most glycolytic enzymes of Trypanosoma brucei have been purified and …

Lipid metabolism is of crucial importance for pathogens. Lipids serve as cellular building
blocks, signalling molecules, energy stores, posttranslational modifiers, and pathogenesis …

CoQ links the sn-glycerol-3-phosphate dehydrogenase and oxidase components of the
cyanide-insensitive, non-cytochrome-mediated respiratory system of bloodstream African …

The relative amounts of ovothiol A (N1-methyl-4-mercaptohistidine) and trypanothione [N1,
N8-bis (glutathionyl) spermidine] have been determined in all life cycle stages of …

The African trypanosome, Trypanosoma brucei brucei, possesses at least two nucleoside
transporter systems designated P1 and P2, the latter being implicated in the selective uptake …