[HTML][HTML] Epigenome-wide association studies: current knowledge, strategies and recommendations

MP Campagna, A Xavier, J Lechner-Scott, V Maltby… - Clinical …, 2021 - Springer
The aetiology and pathophysiology of complex diseases are driven by the interaction
between genetic and environmental factors. The variability in risk and outcomes in these …

[HTML][HTML] ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

DJ Hagler Jr, SN Hatton, MD Cornejo, C Makowski… - Neuroimage, 2019 - Elsevier
Abstract The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing,
nationwide study of the effects of environmental influences on behavioral and brain …

[HTML][HTML] Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan

R Pomponio, G Erus, M Habes, J Doshi, D Srinivasan… - NeuroImage, 2020 - Elsevier
As medical imaging enters its information era and presents rapidly increasing needs for big
data analytics, robust pooling and harmonization of imaging data across diverse cohorts …

Harmonization of cortical thickness measurements across scanners and sites

JP Fortin, N Cullen, YI Sheline, WD Taylor, I Aselcioglu… - Neuroimage, 2018 - Elsevier
With the proliferation of multi-site neuroimaging studies, there is a greater need for handling
non-biological variance introduced by differences in MRI scanners and acquisition …

Evaluation of brain-body health in individuals with common neuropsychiatric disorders

YE Tian, MA Di Biase, PE Mosley, MK Lupton… - JAMA …, 2023 - jamanetwork.com
Importance Physical health and chronic medical comorbidities are underestimated,
inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide …

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years

S Frangou, A Modabbernia, SCR Williams… - Human brain …, 2022 - Wiley Online Library
Delineating the association of age and cortical thickness in healthy individuals is critical
given the association of cortical thickness with cognition and behavior. Previous research …

The normative modeling framework for computational psychiatry

S Rutherford, SM Kia, T Wolfers, C Fraza, M Zabihi… - Nature protocols, 2022 - nature.com
Normative modeling is an emerging and innovative framework for mapping individual
differences at the level of a single subject or observation in relation to a reference model. It …

Statistical harmonization corrects site effects in functional connectivity measurements from multi‐site fMRI data

M Yu, KA Linn, PA Cook, ML Phillips… - Human brain …, 2018 - Wiley Online Library
Acquiring resting‐state functional magnetic resonance imaging (fMRI) datasets at multiple
MRI scanners and clinical sites can improve statistical power and generalizability of results …

[HTML][HTML] Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA

J Radua, E Vieta, R Shinohara, P Kochunov, Y Quidé… - Neuroimage, 2020 - Elsevier
A common limitation of neuroimaging studies is their small sample sizes. To overcome this
hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) …