Organoids are in vitro miniaturized and simplified model systems of organs that have gained
enormous interest for modelling tissue development and disease, and for personalized …

Bone defects repair and regeneration by various causes such as tumor resection, trauma,
degeneration, etc. have always been a key issue in the clinics. As one of the few organs that …

Organoids are self-organizing, expanding 3D cultures derived from stem cells. Using tissue
derived from patients, these miniaturized models recapitulate various aspects of patient …

Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …

Malignant brain tumors remain uniformly fatal, even with the best-to-date treatment. For
Glioblastoma (GBM), the most severe form of brain cancer in adults, the median overall …

Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …

Tumor organoids inherit the genomic and molecular characteristics of the donor tumor,
which not only bridge the gap between genome and phenotype but also circumvent the …

Bioengineered models of human tissues have the potential to revolutionize human health by
providing a translational platform to investigate disease mechanisms and develop new …

Rapid advancements in traditional bone tissue engineering have led to innovation in bone
repair models and the resolution of insurmountable clinical issues like graft scarcity. The …

Head and neck cancers (HNC) are the seventh most prevalent cancer type globally. Despite
their common categorisation, HNCs are a heterogeneous group of malignancies arising in …