There is no effective cure for Chagas disease, which is caused by infection with the
arthropod-borne parasite, Trypanosoma cruzi. In the search for new drugs to treat Chagas …

Covering: up to 2024Ribosomally synthesised and post-translationally modified peptides
(RiPPs) comprise a substantial group of peptide natural products exhibiting noteworthy …

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen
independent lines of Leishmania mexicana and one L. infantum line were selected for …

Natural products comprise valuable sources for new antiparasitic drugs. Here we tested the
effects of a novel β–lapachone derivative on Trypanosoma cruzi parasite survival and …

Chagas disease is a parasitic infection caused by the protozoa Trypanosoma cruzi that
affects about 6 million people in Latin America. Despite its sanitary importance, there are …

Muscular Dystrophies (MDs) are a group of rare inherited genetic muscular pathologies
encompassing a variety of clinical phenotypes, gene mutations and mechanisms of disease …

Polyamines are essential compounds to all living organisms and in the specific case of
Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained …

Trypanosoma congolense is a principal agent causing livestock trypanosomiasis in Africa,
costing developing economies billions of dollars and undermining food security. Only the …

Introducción: la tripanosomiasis americana o enfermedad de Chagas es una de las
parasitosis transmitidas por insectos hematófagos de mayor importancia epidemiológica en …

Background: The American trypanosomiasis, Chagas disease, is a parasitic infection
typically spread by triatomine vectors affecting millions of people all over Latin America …