Lipid nanoparticle (LNP) mediated mRNA delivery in cardiovascular diseases: Advances in genome editing and CAR T cell therapy

S Soroudi, MR Jaafari, L Arabi - Journal of Controlled Release, 2024 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of global mortality among non-
communicable diseases. Current cardiac regeneration treatments have limitations and may …

Representations of lipid nanoparticles using large language models for transfection efficiency prediction

S Moayedpour, J Broadbent, S Riahi, M Bailey… - …, 2024 - academic.oup.com
Results To optimize LNPs, we developed and tested models that enable the virtual
screening of LNPs with high transfection efficiency. Our best method uses the lipid Simplified …