Potential clinical utility of liquid biopsies in ovarian cancer

JW Zhu, P Charkhchi, MR Akbari - Molecular cancer, 2022 - Springer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

Circular RNAs in cancer: opportunities and challenges in the field

LS Kristensen, TB Hansen, MT Venø, J Kjems - Oncogene, 2018 - nature.com
Circular RNA (circRNA) is a novel member of the noncoding cancer genome with distinct
properties and diverse cellular functions, which is being explored at a steadily increasing …

Loss of super-enhancer-regulated circRNA Nfix induces cardiac regeneration after myocardial infarction in adult mice

S Huang, X Li, H Zheng, X Si, B Li, G Wei, C Li… - Circulation, 2019 - Am Heart Assoc
Background: circRNAs (circular RNAs) are emerging as powerful regulators of cardiac
development and disease, but their roles in cardiac regeneration are still unknown. This …

CircRNA: functions and properties of a novel potential biomarker for cancer

S Meng, H Zhou, Z Feng, Z Xu, Y Tang, P Li, M Wu - Molecular cancer, 2017 - Springer
Circular RNAs, a novel class of endogenous noncoding RNAs, are characterized by their
covalently closed loop structures without a 5′ cap or a 3′ Poly A tail. Although the …

Noncoding effects of circular RNA CCDC66 promote colon cancer growth and metastasis

KY Hsiao, YC Lin, SK Gupta, N Chang, L Yen, HS Sun… - Cancer research, 2017 - AACR
Circular RNA (circRNA) is a class of noncoding RNA whose functions remain mostly
unknown. Recent studies indicate circRNA may be involved in disease pathogenesis, but …

Circular RNA–new member of noncoding RNA with novel functions

KY Hsiao, HS Sun, SJ Tsai - Experimental Biology and …, 2017 - journals.sagepub.com
A growing body of evidence indicates that circular RNAs are not simply a side product of
splicing but a new class of noncoding RNAs in higher eukaryotes. The progression for the …

Circles reshaping the RNA world: from waste to treasure

J Liu, T Liu, X Wang, A He - Molecular cancer, 2017 - Springer
A new type of RNAs was identified from genes traditionally thought to express messenger or
linear ncRNA (noncoding RNA) only. They were subsequently named as circRNAs (circular …

The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/FAM65B pathway

LY Zhou, M Zhai, Y Huang, S Xu, T An… - Cell Death & …, 2019 - nature.com
Dysregulated autophagy is associated with many pathological disorders such as
cardiovascular diseases. Emerging evidence has suggested that circular RNAs (circRNAs) …

Function and clinical significance of circRNAs in solid tumors

Y Geng, J Jiang, C Wu - Journal of hematology & oncology, 2018 - Springer
Circular RNA (circRNA) is a new type of endogenous non-coding RNAs (ncRNAs). circRNA
regulates gene expression in many biological processes, and it also participates in the …

[HTML][HTML] CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630

Y Zhang, H Liu, W Li, J Yu, J Li, Z Shen, G Ye… - Aging (albany …, 2017 - ncbi.nlm.nih.gov
Although CircRNA_100269 is a biomarker used to predict cancer recurrence, its expression
and function in gastric cancer (GC) remain unknown. In this study, the expression of …