An insight on synthetic and medicinal aspects of pyrazolo [1, 5-a] pyrimidine scaffold
S Cherukupalli, R Karpoormath… - European journal of …, 2017 - Elsevier
Abstract Pyrazolo [1, 5-a] pyrimidine scaffold is one of the privileged hetrocycles in drug
discovery. Its application as a buliding block for developing drug-like candidates has …
discovery. Its application as a buliding block for developing drug-like candidates has …
Synthesis of 5, 7-diarylpyrazolo [1, 5-a] pyrimidines via KOH mediated tandem reaction of 1H-pyrazol-3-amines and chalcones
An efficient and facile protocol has been developed for the synthesis of pyrazolo [1, 5-a]
pyrimidines through the tandem reaction of 3-aminopyrazoles and chalcones in the …
pyrimidines through the tandem reaction of 3-aminopyrazoles and chalcones in the …
Design and synthesis of novel pyrazolo [1, 5-a] pyrimidine derivatives bearing nitrogen mustard moiety and evaluation of their antitumor activity in vitro and in vivo
M Zhao, H Ren, J Chang, D Zhang, Y Yang… - European Journal of …, 2016 - Elsevier
A series of novel pyrazolo [1, 5-a] pyrimidine derivatives bearing nitrogen mustard moiety
were designed, synthesized and evaluated for their antiproliferative activities against five …
were designed, synthesized and evaluated for their antiproliferative activities against five …
[PDF][PDF] Chalconoid derived heterocycles as potent bioactive molecules: A review
S Sapra, K Sharma, Y Bhalla, KL Dhar - Chem. Sci. J, 2016 - academia.edu
Chemical Sciences Journal Page 1 Volume 7 • Issue 2 • 1000129 Chem Sci J ISSN: 2150-3494
CSJ, an open access journal Research Article Open Access Sapra et al., Chem Sci J 2016 …
CSJ, an open access journal Research Article Open Access Sapra et al., Chem Sci J 2016 …
K2S2O8-promoted C3-thiocyanation of pyrazole [1, 5-a] pyrimidine-7-amines
F Jia, T Sang, J He, Y Liu, J Liu, X Ma, P Liu - Tetrahedron, 2023 - Elsevier
Abstract K 2 S 2 O 8-promoted direct C3-thiocyanation of pyrazolo [1, 5-a] pyrimidin-7-amine
with KSCN is described. A series of C3-thiocyanated products bearing multiple functional …
with KSCN is described. A series of C3-thiocyanated products bearing multiple functional …
An efficient and solvent-free one-pot multi-component synthesis of novel highly substituted pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives …
SK Krishnammagari, BG Cho, JT Kim… - Synthetic …, 2018 - Taylor & Francis
An efficient solvent-free access towards highly substituted pyrido [2′, 3′: 3, 4] pyrazolo [1,
5-a] pyrimidine-3-carbonitrile derivatives has been established through multi-component …
5-a] pyrimidine-3-carbonitrile derivatives has been established through multi-component …
[HTML][HTML] A Simple and Easily Implemented Method for the Regioselective Introduction of Deuterium into Azolo[1,5-a]pyrimidines Molecules
GG Danagulyan, HA Panosyan, VK Gharibyan… - Molecules, 2023 - mdpi.com
A method for the technically easy-to-implement synthesis of deuterium-labeled pyrazolo [1, 5-
a] pyrimidines and 1, 2, 4-triazolo [1, 5-a] pyrimidines have been developed. The …
a] pyrimidines and 1, 2, 4-triazolo [1, 5-a] pyrimidines have been developed. The …
Novel cytotoxic oxovanadium (IV) complexes: Influence of pyrazole‐incorporated heterocyclic scaffolds on their biological response
SB Gajera, JV Mehta, DN Kanthecha… - Applied …, 2017 - Wiley Online Library
Homoleptic VOIV complexes with bidentate heterocycles, namely bipyrazole/pyrimidin‐2‐
amine/triazolopyrimidine derivatives, are novel square pyramidal oxovanadium (IV) …
amine/triazolopyrimidine derivatives, are novel square pyramidal oxovanadium (IV) …
An efficient microwave assisted copper catalyzed C-3 amination of 3-bromopyrazolo [1, 5-a] pyrimidine
TH Iorkula, BA Tolman, JD Singleton, MA Peterson - Tetrahedron Letters, 2023 - Elsevier
Abstract Treatment of 3-bromopyrazolo [1, 5-a] pyrimidine with a variety of 1° or 2°
alkylamines with 20 mol% CuI, 40 mol% l-proline, and Et 3 N (2 equiv) in DMSO under …
alkylamines with 20 mol% CuI, 40 mol% l-proline, and Et 3 N (2 equiv) in DMSO under …
An efficient and green synthesis of novel highly functionalized nitrogen-fused pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine derivatives using recyclable choline …
SK Krishnammagari, YT Jeong - Research on Chemical Intermediates, 2018 - Springer
Choline hydroxide (ChOH) has been found to be a green and efficient basic ionic liquid
catalyst for the synthesis of highly functionalized pyrido [2′, 3′: 3, 4] pyrazolo [1, 5-a] …
catalyst for the synthesis of highly functionalized pyrido [2′, 3′: 3, 4] pyrazolo [1, 5-a] …