Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope

WW Navarre, O Schneewind - Microbiology and molecular biology …, 1999 - Am Soc Microbiol
The cell wall envelope of gram-positive bacteria is a macromolecular, exoskeletal organelle
that is assembled and turned over at designated sites. The cell wall also functions as a …

Complement control protein factor H: the good, the bad, and the inadequate

VP Ferreira, MK Pangburn, C Cortés - Molecular immunology, 2010 - Elsevier
The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …

Complement factor H variant increases the risk of age-related macular degeneration

JL Haines, MA Hauser, S Schmidt, WK Scott, LM Olson… - Science, 2005 - science.org
Age-related macular degeneration (AMD) is a leading cause of visual impairment and
blindness in the elderly whose etiology remains largely unknown. Previous studies identified …

[HTML][HTML] Complement factor H related proteins (CFHRs)

C Skerka, Q Chen, V Fremeaux-Bacchi… - Molecular …, 2013 - Elsevier
Factor H related proteins comprise a group of five plasma proteins: CFHR1, CFHR2,
CFHR3, CFHR4 and CFHR5, and each member of this group binds to the central …

The human complement factor H: functional roles, genetic variations and disease associations

SR de Córdoba, J Esparza-Gordillo, EG de Jorge… - Molecular …, 2004 - Elsevier
Factor H is an essential regulatory protein that plays a critical role in the homeostasis of the
complement system in plasma and in the protection of bystander host cells and tissues from …

The role of inflammation in the pathogenesis of age-related macular degeneration

LA Donoso, D Kim, A Frost, A Callahan… - Survey of …, 2006 - Elsevier
Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is a
complex disease to study because of the potential role of demographic, environmental, and …

The genetics of age-related macular degeneration: a review of progress to date

S Haddad, CA Chen, SL Santangelo… - Survey of ophthalmology, 2006 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness
among older adults in the USA and throughout the developed world. Etiological research …

[HTML][HTML] Regulation of regulators: Role of the complement factor H-related proteins

M Cserhalmi, A Papp, B Brandus, B Uzonyi… - Seminars in …, 2019 - Elsevier
The complement system, while being an essential and very efficient effector component of
innate immunity, may cause damage to the host and result in various inflammatory …

Serum resistance of Acinetobacter baumannii through the binding of factor H to outer membrane proteins

SW Kim, CH Choi, DC Moon, JS Jin… - FEMS microbiology …, 2009 - academic.oup.com
Bacteremia is a common systemic disease caused by Acinetobacter baumannii, an
important hospital-acquired pathogen among critically ill patients. The complement system is …

Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL‐1/reconectin and Factor H

P Kraiczy, C Skerka, M Kirschfink… - European journal of …, 2001 - Wiley Online Library
To understand immune evasion mechanisms of Borrelia burgdorferi we compared serum‐
resistant B. afzelii and serum‐sensitive B. garinii isolates for their capacity toacquire human …