Drug repurposing approach in developing new furosemide analogs as antimicrobial candidates and anti-PBP: design, synthesis, and molecular docking

MF Harras, R Sabour, TA Farghaly, MH Ibrahim - Bioorganic Chemistry, 2023 - Elsevier
Multidrug-resistant microorganisms have become a global health problem, prompting
research into new antimicrobials. Drug repurposing is a new technique in drug discovery …

Indeno[1,2‐b]pyridin‐5‐one derivatives containing azo groups and their hydrazonal precursors: Synthesis, antimicrobial profile, DNA gyrase binding affinity, and …

RM Kassab, ZA Muhammad… - Journal of …, 2024 - Wiley Online Library
The prevalence of germs that are resistant to many antibiotics is rising rapidly the world over.
There is a large group of researchers actively looking for better medicines. Here, we …

HPLC quantitative analysis of two major flavonoids and antimicrobial effectiveness against multi-drug resistant bacteria of different parts of Khaya senegalensis

AS Yassin, SA Abu El Wafa, NG El Menofy… - … and Medical Sciences, 2024 - journals.ekb.eg
Flavonoids are an important group of plant secondary metabolites that are widely used as
powerful antioxidants in the management of a variety of illnesses, including inflammatory …

[PDF][PDF] HPLC analysis of two major flavonoids and antimucrobial effectiveness against t Multi-Drug resistant bacteria of different parts of Khaya senegalensis

N City - J Pharm Med Sci, 2024 - aijpms.journals.ekb.eg
Flavonoids are an important group of plant secondary metabolites that are widely used as
powerful antioxidants in the management of a variety of illnesses, including inflammatory …

Simple and Efficient Synthesis of Highly Functional 2-Oxonicotinonitriles from 2-Chloronicotinonitriles

IN Bardasov, AU Alekseeva, SP Sorokin… - Synlett, 2023 - thieme-connect.com
A simple strategy for the synthesis of 2-oxo-1, 2-dihydropyridine-3-carbonitrile derivatives (2-
oxonicotinonitrile, 3-cyanopyridone) in good yields by substituting the halogen atom with an …