Global aspects of viral glycosylation

I Bagdonaite, HH Wandall - Glycobiology, 2018 - academic.oup.com
Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Exploiting the defensive sugars of HIV-1 for drug and vaccine design

CN Scanlan, J Offer, N Zitzmann, RA Dwek - Nature, 2007 - nature.com
The sustained effort towards developing an antibody vaccine against HIV/AIDS has provided
much of our understanding of viral immunology. It is generally accepted that one of the main …

Research article (new england journal of medicine) severe anemia in malawian children

JCJ Calis, KS Phiri, EB Faragher, BJ Brabin… - Malawi Medical …, 2016 - ajol.info
Background: Severe anemia is a major cause of sickness and death in African children, yet
the causes of anemia in this population have been inadequately studied. Methods: We …

Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect …

M Sagar, X Wu, S Lee, J Overbaugh - Journal of virology, 2006 - Am Soc Microbiol
Over the course of infection, human immunodeficiency virus type 1 (HIV-1) continuously
adapts to evade the evolving host neutralizing antibody responses. Changes in the …

V3: HIV's switch-hitter

O Hartley, PJ Klasse, QJ Sattentau… - AIDS Research & Human …, 2005 - liebertpub.com
The third variable region, V3, of the gp120 surface envelope glycoprotein is an
approximately 35-residue-long, frequently glycosylated, highly variable, disulfide-bonded …

A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization

W Wang, J Nie, C Prochnow, C Truong, Z Jia, S Wang… - Retrovirology, 2013 - Springer
Background Glycans on the human immunodeficiency virus (HIV) envelope glycoprotein
(Env) play an important role in viral infection and evasion of neutralization by antibodies. In …

Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition

M Raska, K Takahashi, L Czernekova… - Journal of Biological …, 2010 - ASBMB
Human immunodeficiency virus type 1 (HIV-1) entry is mediated by the interaction between
a variably glycosylated envelope glycoprotein (gp120) and host-cell receptors …

[HTML][HTML] Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes

MA Naarding, IS Ludwig, F Groot… - The Journal of …, 2005 - Am Soc Clin Investig
DC-specific ICAM3-grabbing non-integrin (DC-SIGN), which is expressed on DCs, can
interact with a variety of pathogens such as HIV-1, hepatitis C, Ebola, cytomegalovirus …

Electrostatic surface potential as a key parameter in virus transmission and evolution: how to manage future virus pandemics in the post-COVID-19 era

J Fantini, F Azzaz, H Chahinian, N Yahi - Viruses, 2023 - mdpi.com
Virus-cell interactions involve fundamental parameters that need to be considered in
strategies implemented to control viral outbreaks. Among these, the surface electrostatic …

Coreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations

W Huang, SH Eshleman, J Toma, S Fransen… - Journal of …, 2007 - Am Soc Microbiol
In human immunodeficiency virus type 1 (HIV-1) subtype B, CXCR4 coreceptor use ranges
from∼ 20% in early infection to∼ 50% in advanced disease. Coreceptor use by non …