Haemochromatosis

LW Powell, RC Seckington, Y Deugnier - The Lancet, 2016 - thelancet.com
Haemochromatosis is now known to be an iron-storage disease with genetic heterogeneity
but with a final common metabolic pathway resulting in inappropriately low production of the …

[PDF][PDF] The pathology of hepatic iron overload: A free radical‐Mediated Process?

BR Bacon, RS Britton - Hepatology, 1990 - Wiley Online Library
Over the past 15 to 20 years much has been learned about genetic (hereditary, primary,
idiopathic) hemochromatosis (GH). Confirmation that the disease is an inherited disorder of …

Insulin resistance–associated hepatic iron overload

MH Mendler, B Turlin, R Moirand, AM Jouanolle… - Gastroenterology, 1999 - Elsevier
Background & Aims: Hepatic iron overload has been reported in various metabolic
conditions, including the insulin-resistance syndrome (IRS) and nonalcoholic steatohepatitis …

Clinical presentation of hemochromatosis: a changing scene

PC Adams, AE Kertesz, LS Valberg - The American journal of medicine, 1991 - Elsevier
Purpose To investigate the changing modes of clinical presentation and diagnosis in 93
patients with familial hemochromatosis and to compare the results with other reports from …

Screening for hemochromatosis

CQ Edwards, JP Kushner - New England Journal of Medicine, 1993 - Mass Medical Soc
In the United States the average daily intake of dietary iron ranges from 10 to 30 mg, but only
about 1 mg is absorbed, to balance precisely the loss due to the sloughing of intact cells …

Diagnosis of hemochromatosis in young subjects: predictive accuracy of biochemical screening tests

ML Bassett, JW Halliday, RA Ferris, LW Powell - Gastroenterology, 1984 - Elsevier
The reliability of serum iron, transferrin saturation, and serum ferritin in the detection of early
iron overload in hemochromatosis was determined in 120 young (< 35 yr old) relatives …

[图书][B] Major issues in the control of iron deficiency

S Gillespie, UNICEF - 1998 - idl-bnc-idrc.dspacedirect.org
Major Issues in the Control of Iron Deficiency Page 1 ARCHIV 108409 Page 2 Major Issues
JDRC.LIb 1D7O in the Control of Iron Deficiency Stuart Gillespie The Micronutrient Initiative …

Hepatic injury in chronic iron overload. Role of lipid peroxidation

BR Bacon, RS Britton - Chemico-biological interactions, 1989 - Elsevier
In both hereditary hemochromatosis and in the various forms of secondary
hemochromatosis, there is a pathologic expansion of body iron stores due mainly to an …

Prevalence of haemochromatosis amongst asymptomatic Australians

BA Leggett, JW Halliday, NN Brown… - British journal of …, 1990 - Wiley Online Library
We determined the prevalence of iron overload due to homozygous haemochromatosis in
an asymptomatic Australian (predominantly Caucasian) population by surveying 1968 …

Screening blood donors for hereditary hemochromatosis: decision analysis model based on a 30-year database

PC Adams, JC Gregor, AE Kertesz, LS Valberg - Gastroenterology, 1995 - Elsevier
Background & Aims: The high prevalence, morbidity, premature death, and benefit of early
diagnosis and treatment make hemochromatosis a prime target for screening in the white …