[HTML][HTML] Reciprocal regulation of mesenchymal stem cells and immune responses

Y Wang, J Fang, B Liu, C Shao, Y Shi - Cell stem cell, 2022 - cell.com
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential

N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells that are emerging as the most
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …

Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics

C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

Immunomodulatory mechanisms and therapeutic potential of mesenchymal stem cells

G Yang, X Fan, Y Liu, P Jie, M Mazhar, Y Liu… - Stem Cell Reviews and …, 2023 - Springer
Mesenchymal stem cells (MSCs) are regarded as highly promising cells for allogeneic cell
therapy, owing to their multipotent nature and ability to display potent and varied functions in …

Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success

G Copp, KP Robb, S Viswanathan - Cellular & Molecular Immunology, 2023 - nature.com
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

Molecular crosstalk between macrophages and mesenchymal stromal cells

HY Stevens, AC Bowles, C Yeago… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSCs) have been widely investigated for regenerative
medicine applications, from treating various inflammatory diseases as a cell therapy to …

[HTML][HTML] Effects of storage media, supplements and cryopreservation methods on quality of stem cells

OD Erol, B Pervin, ME Seker… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Despite a vast amount of different methods, protocols and cryoprotective agents (CPA), stem
cells are often frozen using standard protocols that have been optimized for use with cell …

Principal criteria for evaluating the quality, safety and efficacy of hMSC-based products in clinical practice: current approaches and challenges

JA Guadix, J López-Beas, B Clares, JL Soriano-Ruiz… - Pharmaceutics, 2019 - mdpi.com
Human Mesenchymal Stem Cells (hMSCs) play an important role as new therapeutic
alternatives in advanced therapies and regenerative medicine thanks to their regenerative …

Current advanced therapies based on human mesenchymal stem cells for skin diseases

Á Sierra-Sánchez, T Montero-Vilchez… - Frontiers in Cell and …, 2021 - frontiersin.org
Skin disease may be related with immunological disorders, external aggressions, or genetic
conditions. Injuries or cutaneous diseases such as wounds, burns, psoriasis, and …

Quantitative assessment of the impact of cryopreservation on human bone marrow-derived mesenchymal stem cells: up to 24 h post-thaw and beyond

S Bahsoun, K Coopman, EC Akam - Stem cell research & therapy, 2020 - Springer
Background The effects of cryopreservation on human bone marrow-derived mesenchymal
stem cells (hBM-MSCs) are still ill-defined. In this study, a quantitative approach was …