The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Mitochondria are indispensable for energy metabolism and cell signaling. Mitochondrial
homeostasis is sustained with stabilization of mitochondrial membrane potential, balance of …

A stable mitochondrial pool is crucial for healthy cell function and survival. Altered redox
biology can adversely affect mitochondria through induction of a variety of cell death and …

Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a
global health issue. A comprehensive understanding of the different molecular mechanisms …

Mitochondria are essential organelles for cell metabolism, growth, and function.
Mitochondria in lung cells have important roles in regulating surfactant production …

Background NLRP3‐driven inflammatory responses by circulating and lung‐resident
monocytes are critical drivers of asthma pathogenesis. Autophagy restrains NLRP3‐induced …

Bronchial asthma poses a considerable burden on both individual patients and public
health. Sesamin is a natural lignan that relieves asthma. However, the potential regulatory …

Background Metal components of environmental PM2. 5 are associated with the
exacerbation of allergic diseases like asthma. In our recent hospital-based population study …

Background Despite long-standing recognition in the significance of mucus overproduction
in asthma, its etiology remains poorly understood. Muc5ac is a secretory mucin that has …

Rationale Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, has been
considered as an important regulator for immune diseases. We have previously shown that …