Although vaccination is the main strategy used to control meningococcal disease outbreaks,
mass chemoprophylaxis has also been used as an immediate response to outbreaks, either …

There is evidence that in infected cells in vitro the meningococcal HrpA/HrpB two-partner
secretion system (TPS) mediates the exit of bacteria from the internalization vacuole and the …

The effect of Bacillus subtilis exposure to the human spaceflight environment on growth,
mutagenic frequency, and spectrum of mutations to rifampicin resistance (RifR) was …

Objectives To establish the role of specific, non-synonymous SNPs in the RNA polymerase β
subunit (rpoB) gene in reducing the susceptibility of Clostridium difficile to fidaxomicin and to …

Acinetobacter baumannii is a major cause of antibiotic-resistant nosocomial infections
worldwide. In this study, several rifampin-resistant spontaneous mutants obtained from the …

Rifampicin is a broad-spectrum antibiotic that binds to the bacterial RNA polymerase
(RNAP), compromising DNA transcription. Rifampicin resistance is common in several …

Background Riemerella anatipestifer (R. anatipestifer) is one of the most important poultry
pathogens worldwide, with associated infections causing significant economic losses …

The improper use and abuse of antibiotics have led to an increase in multidrug-resistant
(MDR) bacteria resulting in a failure of standard antibiotic therapies. To date, this …

Although we previously reported that some meningococcal isolates in Japan were resistant
to penicillin (PCG) and ciprofloxacin (CIP), the antibiotic susceptibilities of Neisseria …

Antibiotic resistance is becoming a severe obstacle in the fight against acute and chronic
infectious diseases that accompany most degenerative illnesses from neoplasia to osteo …