Molecular Mechanisms of Valproic Acid Action on Signalling Systems and Brain Functions

AN Tursunov, DS Vasilyev, NN Nalivaeva - Journal of Evolutionary …, 2023 - Springer
Valproic acid (valproate, VA) has been widely used as an antiepileptic agent for several
decades, as well as in the treatment of bipolar affective disorder. For many years, the ability …

[HTML][HTML] Analysis of the global burden of disease study highlights the global, regional, and national trends of idiopathic epilepsy epidemiology from 1990 to 2019

Y Zhang, X Kong, J Lv, CH Yang, X Li, X Yang… - Preventive Medicine …, 2023 - Elsevier
Epilepsy is a profound disorder, accounting for roughly 1% of the global disease burden. It
can result in premature death and significant disability. To comprehensively understand the …

Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients

L Guo, YJ Qi, H Tan, D Dai, R Balesar, A Sluiter… - …, 2022 - thelancet.com
Background Oxytocin (OXT) and corticotropin-releasing hormone (CRH) are both produced
in hypothalamic paraventricular nucleus (PVN). Central CRH may cause depression-like …

[HTML][HTML] Pain sensitivity related to gamma oscillation of parvalbumin interneuron in primary somatosensory cortex in Dync1i1−/− mice

Z Guo, H Ni, Z Cui, Z Zhu, J Kang, D Wang, Z Ke - Neurobiology of Disease, 2023 - Elsevier
Cytoplasmic dynein is an important intracellular motor protein that plays an important role in
neuronal growth, axonal polarity formation, dendritic differentiation, and dendritic spine …

Roles and mechanisms of leptomeningeal collaterals in human distal MCA territory ischemia

X Zou, S Mei, Z Wu, K Song, Y Xu, J Hu, L Chen, Y Mao - bioRxiv, 2024 - biorxiv.org
Objective: Leptomeningeal collaterals (LMCs) provided hemodynamic support and
reperfusion during acute ischemic stroke (AIS). Although regulation details have been …

[PDF][PDF] Royal Netherlands Academy of Arts and Sciences (KNAW)

MRJ Mason, S Erp, K Wolzak, A Behrens, G Raivich… - 2021 - pure.knaw.nl
The regeneration-associated gene (RAG) expression program is activated in injured
peripheral neurons after axotomy and enables long-distance axon re-growth. Over 1000 …