Epidemiological and biological plausibility studies support a cause-and-effect relationship
between increased levels of physical activity or cardiorespiratory fitness and reduced …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Importance Adverse cardiovascular findings associated with habitual vigorous exercise
have raised new questions regarding the benefits of exercise and fitness. Objective To …

Importance The 2008 Physical Activity Guidelines for Americans recommended a minimum
of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic …

The benefits of exercise are irrefutable. Individuals engaging in regular exercise have a
favourable cardiovascular risk profile for coronary artery disease and reduce their risk of …

Multiple epidemiological studies document that habitual physical activity reduces the risk of
atherosclerotic cardiovascular disease (ASCVD), and most demonstrate progressively lower …

Accumulation of dysfunctional and damaged cellular proteins and organelles occurs during
aging, resulting in a disruption of cellular homeostasis and progressive degeneration and …

Habitual physical activity and regular exercise training improve cardiovascular health and
longevity. A physically active lifestyle is, therefore, a key aspect of primary and secondary …

The present update is dedicated to the evolution of the interaction between heart failure (HF)
and exercise and how the scientific community has handled it. Indeed, on the one hand, HF …

Exercise confers a plethora of health benefits that are well documented, whereas physical
inactivity is a leading risk factor for cardiovascular morbidity and mortality. The dose of …