Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …
The role of epigenetic change in autism spectrum disorders
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …
disorders characterized by problems with social communication, social interaction, and …
Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes
AC Lionel, K Tammimies, AK Vaags… - Human molecular …, 2014 - academic.oup.com
Rare copy number variants (CNVs) disrupting ASTN2 or both ASTN2 and TRIM32 have
been reported at 9q33. 1 by genome-wide studies in a few individuals with …
been reported at 9q33. 1 by genome-wide studies in a few individuals with …
Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia
ND Merner, MR Chandler, C Bourassa… - Frontiers in cellular …, 2015 - frontiersin.org
Many encoded gene products responsible for neurodevelopmental disorders (NDs) like
autism spectrum disorders (ASD), schizophrenia (SCZ), intellectual disability (ID), and …
autism spectrum disorders (ASD), schizophrenia (SCZ), intellectual disability (ID), and …
An inside job: how endosomal Na+/H+ exchangers link to autism and neurological disease
Autism imposes a major impediment to childhood development and a huge emotional and
financial burden on society. In recent years, there has been rapidly accumulating genetic …
financial burden on society. In recent years, there has been rapidly accumulating genetic …
Mesenchymal stem cell transplantation promotes neurogenesis and ameliorates autism related behaviors in BTBR mice
Autism spectrum disorders (ASD) are characterized by social communication deficits,
cognitive rigidity, and repetitive stereotyped behaviors. Mesenchymal stem cells (MSC) have …
cognitive rigidity, and repetitive stereotyped behaviors. Mesenchymal stem cells (MSC) have …
[HTML][HTML] Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and …
R Sharma, S Rahi, S Mehan - Toxicology reports, 2019 - Elsevier
Autism is the category used within the newest edition of the diagnostic and statistical manual
of neurodevelopmental disorders. Autism is a spectrum of disorder where a variety of …
of neurodevelopmental disorders. Autism is a spectrum of disorder where a variety of …
Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments
T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …
relationship between small-scale dendrite morphological abnormalities (shape, density of …
[HTML][HTML] Cux1 enables interhemispheric connections of layer II/III neurons by regulating Kv1-dependent firing
FM Rodríguez-Tornos, CG Briz, LA Weiss… - Neuron, 2016 - cell.com
Neuronal subtype-specific transcription factors (TFs) instruct key features of neuronal
function and connectivity. Activity-dependent mechanisms also contribute to wiring and …
function and connectivity. Activity-dependent mechanisms also contribute to wiring and …
Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex
Background Genetic studies in autism have pinpointed a heterogeneous group of loci and
genes. Further, environment may be an additional factor conferring susceptibility to autism …
genes. Further, environment may be an additional factor conferring susceptibility to autism …