Poloxamer hydrogels for biomedical applications
E Russo, C Villa - Pharmaceutics, 2019 - mdpi.com
This review article focuses on thermoresponsive hydrogels consisting of poloxamers which
are of high interest for biomedical application especially in drug delivery for ophthalmic …
are of high interest for biomedical application especially in drug delivery for ophthalmic …
Adhesive hydrogels in osteoarthritis: From design to application
WL Duan, LN Zhang, R Bohara… - Military Medical …, 2023 - Springer
Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …
of the global population and more than 500 million people worldwide. One research frontier …
Thermosensitive hydrogel based on PEO–PPO–PEO poloxamers for a controlled in situ release of recombinant adeno‐associated viral vectors for effective gene …
Advanced biomaterial‐guided delivery of gene vectors is an emerging and highly attractive
therapeutic solution for targeted articular cartilage repair, allowing for a controlled and …
therapeutic solution for targeted articular cartilage repair, allowing for a controlled and …
Biomaterial-guided delivery of gene vectors for targeted articular cartilage repair
M Cucchiarini, H Madry - Nature Reviews Rheumatology, 2019 - nature.com
Articular cartilage defects are prevalent and are potentially involved in the initiation of
osteoarthritis, yet the lack of efficient therapeutic options to treat cartilage defects represents …
osteoarthritis, yet the lack of efficient therapeutic options to treat cartilage defects represents …
Nanogels for regenerative medicine
MA Grimaudo, A Concheiro… - Journal of Controlled …, 2019 - Elsevier
Nanogels have been widely explored for drug delivery, but their applications in the tissue
engineering field are still quite recent. Regenerative medicine also demands controlled …
engineering field are still quite recent. Regenerative medicine also demands controlled …
[HTML][HTML] Poloxamer-chitosan-based Naringenin nanoformulation used in brain targeting for the treatment of cerebral ischemia
Objective Here, the aim is to improve the bioavailability of Naringenin (NRG) in brain and to
establish the highest remedial benefit from a novel anti-ischemic medicine ie NRG. Methods …
establish the highest remedial benefit from a novel anti-ischemic medicine ie NRG. Methods …
Injectable hydrogels and nanocomposite hydrogels for cartilage regeneration
Cartilage loss due to age‐related degeneration and mechanical trauma is a significant and
challenging problem in the field of surgical medicine. Unfortunately, cartilage tissue can be …
challenging problem in the field of surgical medicine. Unfortunately, cartilage tissue can be …
[HTML][HTML] Recent advances in polymeric biomaterials-based gene delivery for cartilage repair
Untreated articular cartilage damage normally results in osteoarthritis and even disability
that affects millions of people. However, both the existing surgical treatment and tissue …
that affects millions of people. However, both the existing surgical treatment and tissue …
Materials promoting viral gene delivery
K Kaygisiz, CV Synatschke - Biomaterials Science, 2020 - pubs.rsc.org
Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …
mutations by introducing new genetic information to cells either to correct a faulty gene or to …
A novel indomethacin/methotrexate/MMP-9 siRNA in situ hydrogel with dual effects of anti-inflammatory activity and reversal of cartilage disruption for the synergistic …
N Yin, X Tan, H Liu, F He, N Ding, J Gou, T Yin, H He… - Nanoscale, 2020 - pubs.rsc.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammatory cell
infiltration, and cartilage and bone disruption, which ultimately leads to loss of joint function …
infiltration, and cartilage and bone disruption, which ultimately leads to loss of joint function …