With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …

Lead toxicity is a major public health issue in developed and developing countries. Both
acute and chronic lead exposure has the potential to cause many deleterious systematic …

Neurodegenerative diseases including Alzheimer (AD) and Parkinson (PD) have attracted
attention in last decades due to their high incidence worldwide. The etiology of these …

Long-lasting memories require specific gene expression programmes that are, in part,
orchestrated by epigenetic mechanisms. Of the epigenetic modifications identified in …

Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Handbook on the Toxicology of Metals, Volume II: Specific Metals, Fifth Edition provides
complete coverage of 38 individual metals and their compounds. This volume is the second …

Alzheimer's dis ease (AD) is a leading cause of mortality in the developed world with 70%
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …

BACKGROUND: Subjective cognitive impairment (SCI) in older persons without manifest
symptomatology is a common condition with a largely unclear prognosis. We hypothesized …

Neurodegeneration describes the loss of neuronal structure and function. Numerous
neurodegenerative diseases are associated with neurodegeneration. Many are rare and …