Blood-based biomarkers for Alzheimer's disease diagnosis and progression: an overview

A Varesi, A Carrara, VG Pires, V Floris, E Pierella… - Cells, 2022 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disease characterized by
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …

Targeting epigenetics: a novel promise for Alzheimer's disease treatment

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing Research Reviews, 2023 - Elsevier
So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

Anti-inflammatory effects of B vitamins protect against tau hyperphosphorylation and cognitive impairment induced by 1, 2 diacetyl benzene: an in vitro and in silico …

HD Nguyen, WH Jo, NHM Hoang, MS Kim - International …, 2022 - Elsevier
Abstract 1, 2 diacetyl benzene (DAB) penetrates the blood–brain barrier, causing
neuroinflammation, tau hyperphosphorylation, and cognitive impairment. Converging …

A review on omics-based biomarkers discovery for Alzheimer's disease from the bioinformatics perspectives: statistical approach vs machine learning approach

MS Tan, PL Cheah, AV Chin, LM Looi… - Computers in biology and …, 2021 - Elsevier
Alzheimer's Disease (AD) is a neurodegenerative disease that affects cognition and is the
most common cause of dementia in the elderly. As the number of elderly individuals …

OViTAD: Optimized vision transformer to predict various stages of Alzheimer's disease using resting-state fMRI and structural MRI data

S Sarraf, A Sarraf, DD DeSouza, JAE Anderson… - Brain Sciences, 2023 - mdpi.com
Advances in applied machine learning techniques for neuroimaging have encouraged
scientists to implement models to diagnose brain disorders such as Alzheimer's disease at …

Beyond the amyloid hypothesis: how current research implicates autoimmunity in Alzheimer's disease pathogenesis

MK Chatanaka, D Sohaei, EP Diamandis… - Critical Reviews in …, 2023 - Taylor & Francis
The amyloid hypothesis has so far been at the forefront of explaining the pathogenesis of
Alzheimer's Disease (AD), a progressive neurodegenerative disorder that leads to cognitive …

[HTML][HTML] Cognitive dysfunction associated with COVID-19: Prognostic role of circulating biomarkers and microRNAs

M Alvarez, E Trent, BDS Goncalves… - Frontiers in Aging …, 2022 - frontiersin.org
COVID-19 is renowned as a multi-organ disease having subacute and long-term effects with
a broad spectrum of clinical manifestations. The evolving scientific and clinical evidence …

The role of microRNAs in epigenetic regulation of signaling pathways in neurological pathologies

PP Tregub, I Ibrahimli, AS Averchuk… - International journal of …, 2023 - mdpi.com
In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

Artificial intelligence predictor for Alzheimer's disease trained on blood transcriptome: The role of oxidative stress

L Chiricosta, S D'Angiolini, A Gugliandolo… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is an incurable neurodegenerative disease diagnosed by
clinicians through healthcare records and neuroimaging techniques. These methods lack …

[HTML][HTML] A review of miRNAs as biomarkers and effect of dietary modulation in obesity associated cognitive decline and neurodegenerative disorders

M Perdoncin, A Konrad, JR Wyner, S Lohana… - Frontiers in Molecular …, 2021 - frontiersin.org
There has been a progressive increase in the prevalence of obesity and its comorbidities
such as type 2 diabetes and cardiovascular diseases worldwide. Recent studies have …