Candida Biofilms: Threats, Challenges, and Promising Strategies
M Cavalheiro, MC Teixeira - Frontiers in medicine, 2018 - frontiersin.org
Candida species are fungal pathogens known for their ability to cause superficial and
systemic infections in the human host. These pathogens are able to persist inside the host …
systemic infections in the human host. These pathogens are able to persist inside the host …
Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis
C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …
Candida albicans targets that potentially synergize with fluconazole
H Lu, M Shrivastava, M Whiteway… - Critical reviews in …, 2021 - Taylor & Francis
Fluconazole has characteristics that make it widely used in the clinical treatment of C.
albicans infections. However, fluconazole has only a fungistatic activity in C. albicans …
albicans infections. However, fluconazole has only a fungistatic activity in C. albicans …
Transcriptional control of hyphal morphogenesis in Candida albicans
S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …
in humans. A morphological switch between unicellular budding yeast and multicellular …
Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals
Antifungal resistance of Candida species is a clinical problem in the management of
diseases caused by these pathogens. In this study we identified from a collection of 423 …
diseases caused by these pathogens. In this study we identified from a collection of 423 …
Transcriptional Circuits Regulating Developmental Processes in Candida albicans
DL Rodriguez, MM Quail, AD Hernday… - Frontiers in Cellular and …, 2020 - frontiersin.org
Candida albicans is a commensal member of the human microbiota that colonizes multiple
niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary …
niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary …
Multi-omics Signature of Candida auris, an Emerging and Multidrug-Resistant Pathogen
D Zamith-Miranda, HM Heyman, LG Cleare… - …, 2019 - Am Soc Microbiol
Candida auris is a recently described pathogenic fungus that is causing invasive outbreaks
on all continents. The fungus is of high concern given the numbers of multidrug-resistant …
on all continents. The fungus is of high concern given the numbers of multidrug-resistant …
A Versatile Overexpression Strategy in the Pathogenic Yeast Candida albicans: Identification of Regulators of Morphogenesis and Fitness
Candida albicans is the most frequently encountered human fungal pathogen, causing both
superficial infections and life-threatening systemic diseases. Functional genomic studies …
superficial infections and life-threatening systemic diseases. Functional genomic studies …
Analysis of a fungus‐specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation
R Schillig, J Morschhäuser - Molecular microbiology, 2013 - Wiley Online Library
The zinc cluster proteins are a family of transcription factors that are unique to the fungal
kingdom. In the pathogenic yeast C andida albicans, zinc cluster transcription factors control …
kingdom. In the pathogenic yeast C andida albicans, zinc cluster transcription factors control …
Functional genomic screening reveals core modulators of echinocandin stress responses in Candida albicans
Candida albicans is a leading cause of death due to fungal infection. Treatment of systemic
candidiasis often relies on echinocandins, which disrupt cell wall synthesis. Resistance is …
candidiasis often relies on echinocandins, which disrupt cell wall synthesis. Resistance is …