Cancer immunotherapy is a validated and critically important approach for treating patients
with cancer. Given the vast research and clinical investigation efforts dedicated to advancing …

Inclusion body myositis (IBM) is often viewed as an enigmatic disease with uncertain
pathogenic mechanisms and confusion around diagnosis, classification and prospects for …

In triple-negative breast cancer (TNBC), the benefit of combining chemotherapy with
checkpoint inhibitors is still not very clear. We utilize single-cell RNA-and ATAC-sequencing …

Rationale: There remains uncertainty about the role of corticosteroids in sepsis with clear
beneficial effects on shock duration, but conflicting survival effects. Two transcriptomic …

Glioblastoma is the most common primary malignant brain tumour. Survival is poor and
improved treatment options are urgently needed. Although immunotherapies have emerged …

Objectives Comorbidities have significant indications for the disease outcome of COVID-19,
however which underlying diseases that contribute the most to aggravate the conditions of …

Background Critically ill COVID-19 patients are highly susceptible to opportunistic fungal
infection due to many factors, including virus-induced immune dysregulation, host-related …

Glioblastoma (WHO grade IV glioma) is the most common malignant primary brain tumor in
adults. Survival has remained largely static for decades, despite significant efforts to develop …

The importance of Zn for human health becomes obvious during Zn deficiency. Even mild
insufficiencies of Zn cause alterations in haematopoiesis and immune functions, resulting in …

Background There has been a significant increase in the use of immunotherapy and
cannabis recently, two modalities that have immunomodulatory effects and may have …