Common variable immunodeficiency disorders (CVID), a heterogeneous group of inborn
errors of immunity, is the most common symptomatic primary immunodeficiency disorder …

The advent of next-generation sequencing (NGS) and 'omic'technologies has revolutionized
the field of genetics, and its implementation in health care has the potential to realize …

Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency characterized by low immunoglobulin (Ig) G and IgA, and/or IgM. In …

Background Genome-wide association studies have shown a pattern of rare copy number
variations and single nucleotide polymorphisms in patients with common variable …

Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by
recurrent bacterial infections and defined by reduced levels of IgG, IgA, and/or IgM …

Predominantly antibody deficiency (PAD) is the most prevalent form of primary
immunodeficiency, and is characterized by broad clinical, immunological and genetic …

Laboratory tests are essential for clinicians to reach an accurate diagnosis and informing
appropriate treatments. The expansion in the use of immunotherapies has highlighted the …

Ultrasonic vocalizations (USVs) serve important communicative functions in rodents.
Different types of USVs can be triggered in the sender, for example, by maternal separation …

Primary immunodeficiencies (PIDs) are a group of rare genetic diseases resulting in the
impairment of one or more functions of the human immune system. Common variable …

Pathogens and infectious diseases have imposed exceptionally strong selective pressure
on ancient and modern human genomes and contributed to the current variation in many …