Glucose transporters in cancer–from tumor cells to the tumor microenvironment

PB Ancey, C Contat, E Meylan - The FEBS journal, 2018 - Wiley Online Library
Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular
glucose usage. The upregulation of GLUT s has been reported in numerous cancer types as …

Structure, function and regulation of mammalian glucose transporters of the SLC2 family

GD Holman - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
The SLC2 genes code for a family of GLUT proteins that are part of the major facilitator
superfamily (MFS) of membrane transporters. Crystal structures have recently revealed how …

[PDF][PDF] Cell culture media: a review

M Arora - Mater methods, 2013 - researchgate.net
Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …

The protein family of glucose transport facilitators: It's not only about glucose after all

R Augustin - IUBMB life, 2010 - Wiley Online Library
The protein family of facilitative glucose transporters comprises 14 isoforms that share
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …

[HTML][HTML] Hepatic expression and cellular distribution of the glucose transporter family

S Karim, DH Adams, PF Lalor - World journal of gastroenterology …, 2012 - ncbi.nlm.nih.gov
Glucose and other carbohydrates are transported into cells using members of a family of
integral membrane glucose transporter (GLUT) molecules. To date 14 members of this …

Nutritional effects on oocyte and embryo development in mammals: implications for reproductive efficiency and environmental sustainability

CJ Ashworth, LM Toma… - … Transactions of the …, 2009 - royalsocietypublishing.org
The environment in which a breeding female lives prior to conception and during the early
stages of her pregnancy has striking effects on oocytes developing in the ovarian follicle and …

Potential role of sugar transporters in cancer and their relationship with anticancer therapy

MB Calvo, A Figueroa, EG Pulido… - International journal …, 2010 - Wiley Online Library
Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their
hydrophilic nature, cells use a number of transporter proteins to introduce sugars through …

[HTML][HTML] MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression

X Fei, M Qi, B Wu, Y Song, Y Wang, T Li - FEBS letters, 2012 - Elsevier
It has been reported that expression of glucose transporter member 3 (GLUT3) is up-
regulated in bladder cancers. However, the regulating mechanism remains unknown. Here …

[HTML][HTML] Influences of rare copy-number variation on human complex traits

MLA Hujoel, MA Sherman, AR Barton, RE Mukamel… - Cell, 2022 - cell.com
The human genome contains hundreds of thousands of regions harboring copy-number
variants (CNV). However, the phenotypic effects of most such polymorphisms are unknown …

Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis

N Takata, JM Miska, MA Morgan, P Patel… - Nature …, 2023 - nature.com
Mammalian retinal metabolism favors aerobic glycolysis. However, the role of glycolytic
metabolism in retinal morphogenesis remains unknown. We report that aerobic glycolysis is …