An overview of circulating pulmonary arterial hypertension biomarkers

J Santos-Gomes, I Gandra, R Adão, F Perros… - Frontiers in …, 2022 - frontiersin.org
Pulmonary arterial hypertension (PAH), also known as Group 1 Pulmonary Hypertension
(PH), is a PH subset characterized by pulmonary vascular remodeling and pulmonary …

Progenitor/stem cells in vascular remodeling during pulmonary arterial hypertension

F Dierick, J Solinc, J Bignard, F Soubrier, S Nadaud - Cells, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is characterized by an important occlusive vascular
remodeling with the production of new endothelial cells, smooth muscle cells …

Tanshinone II A attenuates TNF-α-induced expression of VCAM-1 and ICAM-1 in endothelial progenitor cells by blocking activation of NF-κB

JX Yang, YY Pan, JH Ge, B Chen, W Mao… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Tanshinone IIA (Tan IIA) is effective in the treatment of inflammation and
atherosclerosis. The adhesion of inflammatory cells to vascular endothelium plays important …

Genetic delivery and gene therapy in pulmonary hypertension

N Rai, M Shihan, W Seeger, RT Schermuly… - International Journal of …, 2021 - mdpi.com
Pulmonary hypertension (PH) is a progressive complex fatal disease of multiple etiologies.
Hyperproliferation and resistance to apoptosis of vascular cells of intimal, medial, and …

[HTML][HTML] Probucol protects endothelial progenitor cells against oxidized low-density lipoprotein via suppression of reactive oxygen species formation in vivo

Q Zhang, L Chen, Z Si, H Bu, CA Narasimhulu… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Oxidized low-density lipoprotein (ox-LDL) is a major component of
hyperlipidemia and contributes to atherosclerosis. Endothelial progenitor cells (EPCs) play …

Circulating Biomarkers in Pulmonary Arterial Hypertension: An Update

M Correale, L Tricarico, EML Bevere, F Chirivì… - Biomolecules, 2024 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare subtype of group 1 pulmonary hypertension
(PH) diseases, characterized by high pulmonary artery pressure leading to right ventricular …

Erythropoietin attenuates pulmonary vascular remodeling in experimental pulmonary arterial hypertension through interplay between endothelial progenitor cells and …

RLE Van Loon, B Bartelds, FA Wagener… - Frontiers in …, 2015 - frontiersin.org
Background Pulmonary arterial hypertension (PAH) is a pulmonary vascular disease with a
high mortality, characterized by typical angio-proliferative lesions. Erythropoietin (EPO) …

Regenerative cell therapy for pulmonary arterial hypertension in animal models: a systematic review

CM Suen, DJ Stewart, J Montroy, C Welsh… - Stem Cell Research & …, 2019 - Springer
Background Pulmonary arterial hypertension (PAH) is a rare disease characterized by
widespread loss of the pulmonary microcirculation and elevated pulmonary arterial …

Metabolic gene therapy in a canine with pulmonary hypertension secondary to degenerative mitral valve disease

MG Katz, DG Ohad, P Putter, N Shtraizent… - Frontiers in Veterinary …, 2024 - frontiersin.org
Myxomatous mitral valve disease (MMVD) stands out as the most prevalent acquired canine
heart disease. Its occurrence can reach up to 40% in small breed dogs and escalates in …

Protective effect of nicotinamide and l-arginine against monocrotaline-induced pulmonary hypertension in rats: gender dependence

K Sztormowska-Achranowicz, Z Jankowski… - Pharmacological …, 2020 - Springer
Background The purpose of this paper was to examine the effects of nicotinamide (ND) and l-
arginine (l-ARG) on pulmonary vascular and heart changes induced by pulmonary …