Evolution of pathogen tolerance and emerging infections: A missing experimental paradigm

S Seal, G Dharmarajan, I Khan - Elife, 2021 - elifesciences.org
Researchers worldwide are repeatedly warning us against future zoonotic diseases
resulting from humankind's insurgence into natural ecosystems. The same zoonotic …

Intracellular Interactions Between Arboviruses and Wolbachia in Aedes aegypti

JIL Reyes, Y Suzuki, T Carvajal… - Frontiers in Cellular …, 2021 - frontiersin.org
Aedes aegypti is inherently susceptible to arboviruses. The geographical expansion of this
vector host species has led to the persistence of Dengue, Zika, and Chikungunya human …

Comprehensive Quantitative Proteome Analysis of Aedes aegypti Identifies Proteins and Pathways Involved in Wolbachia pipientis and Zika Virus Interference …

M Martins, LFC Ramos, JR Murillo, A Torres… - Frontiers in …, 2021 - frontiersin.org
Zika virus (ZIKV) is a global public health emergency due to its association with
microcephaly, Guillain-Barré syndrome, neuropathy, and myelitis in children and adults. A …

Wolbachia-mediated resistance to Zika virus infection in Aedes aegypti is dominated by diverse transcriptional regulation and weak evolutionary pressures

EC Boehm, AS Jaeger, HJ Ries… - PLoS neglected …, 2023 - journals.plos.org
A promising candidate for arbovirus control and prevention relies on replacing arbovirus-
susceptible Aedes aegypti populations with mosquitoes that have been colonized by the …

Differences in gene expression in field populations of Wolbachia-infected Aedes aegypti mosquitoes with varying release histories in northern Australia

BMCR Wimalasiri-Yapa, B Huang… - PLoS Neglected …, 2023 - journals.plos.org
Aedes aegypti is the principal mosquito vector of dengue, yellow fever, Zika and
chikungunya viruses. The w Mel strain of the endosymbiotic bacteria Wolbachia pipientis …

Interspecies Isobaric Labeling-Based Quantitative Proteomics Reveals Protein Changes in the Ovary of Aedes aegypti Coinfected With ZIKV and Wolbachia

LFC Ramos, M Martins, JR Murillo… - Frontiers in Cellular …, 2022 - frontiersin.org
Zika is a vector-borne disease caused by an arbovirus (ZIKV) and overwhelmingly
transmitted by Ae. aegypti. This disease is linked to adverse fetal outcomes, mostly …

The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO

HLC Dutra, SA Ford, SL Allen… - PLoS neglected …, 2021 - journals.plos.org
Wolbachia is currently at the forefront of global efforts to control arbovirus transmission from
the vector Aedes aegypti. The use of Wolbachia relies on two phenotypes—cytoplasmic …

Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities

AJ Mejia, L Jimenez, HLC Dutra, R Perera, EA McGraw - Heredity, 2022 - nature.com
Wolbachia is an insect endosymbiont being used for biological control in the mosquito
Aedes aegypti because it causes cytoplasmic incompatibility (CI) and limits viral replication …

Altered gene expression profile of Wolbachia pipientis wAlbB strain following transinfection from its native host Aedes albopictus to Aedes aegypti cells

C Bishop, S Asgari - Molecular Microbiology, 2021 - Wiley Online Library
Wolbachia is an obligate intracellular bacterial symbiont prevalent among arthropods and
nematodes. To survive and reproduce, Wolbachia interacts with and modifies host …

Alpha‐mannosidase‐2 modulates arbovirus infection in a pathogen‐ and Wolbachia‐specific manner in Aedes aegypti mosquitoes

N Urakova, RE Joseph, A Huntsinger… - Insect Molecular …, 2024 - Wiley Online Library
Multiple Wolbachia strains can block pathogen infection, replication and/or transmission in
Aedes aegypti mosquitoes under both laboratory and field conditions. However, Wolbachia …