This review is focused on the mechanisms that regulate health, disease and aging redox
status, the signal pathways that counteract oxidative and reductive stress, the role of food …

Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with insulin resistance
and hyperglycemia. Chronic exposure to a T2DM microenvironment with hyperglycemia …

Kidney is one of the most vulnerable organs in sepsis, resulting in sepsis-associated acute
kidney injury (SA-AKI), which brings about not only morbidity but also mortality of sepsis …

Background: Kickboxing is a combat sport where athletes require constant supervision of a
coach. The outbreak of the pandemic caused by SARS-CoV-2 has led to a crisis in many …

It is now established that adipose tissue, skeletal muscle, and heart are endocrine organs
and secrete in normal and in pathological conditions several molecules, called, respectively …

Recent studies found that irisin, a newly discovered skeletal muscle-derived myokine during
exercise, is also synthesized in various tissues of different species and protects against …

Irisin is produced by a proteolytic cleavage of fibronectin type III domain-containing protein 5
(FNDC5) and has emerged as a potential mediator of exercise-induced energy metabolism …

This study examined the effects of a nine-week intervention of four different high-intensity
training modalities [high-intensity functional training (HIFT), high-intensity interval training …

Each person's body is host to a large number and variety of gut microbiota, which has been
described as the second genome and plays an important role in the body's metabolic …

Neurons suffer detrimental effects from β‐amyloid toxicity in Alzheimer's disease. The
exercise hormone, irisin, is found to induce a neuroprotective gene program and facilitates …