Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence
BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …
Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes
P Hernández-Vargas, M Muñoz… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Successful embryo implantation is a complex process that requires the
coordination of a series of events, involving both the embryo and the maternal endometrium …
coordination of a series of events, involving both the embryo and the maternal endometrium …
Integrated strategy for accurately screening biomarkers based on metabolomics coupled with network pharmacology
W Zhang, Y Chen, H Jiang, J Yang, Q Wang, Y Du… - Talanta, 2020 - Elsevier
Screening diagnostic biomarkers can be challenging due to the complexity of traditional
Chinese medicine (TCM) and ambiguous pharmacological mechanisms. In this study, we …
Chinese medicine (TCM) and ambiguous pharmacological mechanisms. In this study, we …
Follicular fluid: a powerful tool for the understanding and diagnosis of polycystic ovary syndrome
AT Brinca, AC Ramalhinho, Â Sousa, AH Oliani… - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) represents one of the leading causes of anovulatory
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …
[HTML][HTML] Why are multiple pregnancy rates and single embryo transfer rates so different globally, and what do we do about it?
GD Adamson, RJ Norman - Fertility and Sterility, 2020 - Elsevier
In the early years of in vitro fertilization, overall pregnancy rates were low, and it was
considered necessary to transfer more than one embryo to increase the chances of …
considered necessary to transfer more than one embryo to increase the chances of …
Capture and metabolomic analysis of the human endometrial epithelial organoid secretome
CA Simintiras, P Dhakal, C Ranjit… - Proceedings of the …, 2021 - National Acad Sciences
Suboptimal uterine fluid (UF) composition can lead to pregnancy loss and likely contributes
to offspring susceptibility to chronic adult-onset disorders. However, our understanding of …
to offspring susceptibility to chronic adult-onset disorders. However, our understanding of …
Proteomics and metabolomics—Current and future perspectives in clinical andrology
MK Panner Selvam, R Finelli, A Agarwal… - Andrologia, 2021 - Wiley Online Library
Proteomics and metabolomics are emerging as promising tools to investigate the molecular
mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in …
mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in …
Chemometric-guided approaches for profiling and authenticating botanical materials
EJ Abraham, JJ Kellogg - Frontiers in Nutrition, 2021 - frontiersin.org
Botanical supplements with broad traditional and medicinal uses represent an area of
growing importance for American health management; 25% of US adults use dietary …
growing importance for American health management; 25% of US adults use dietary …
Metabolomic biomarkers for detection, prognosis and identifying recurrence in endometrial cancer
Metabolic reprogramming is increasingly recognised as one of the defining hallmarks of
tumorigenesis. There is compelling evidence to suggest that endometrial cancer develops …
tumorigenesis. There is compelling evidence to suggest that endometrial cancer develops …
Extracellular vesicles in the oviduct: progress, challenges and implications for the reproductive success
C Almiñana, S Bauersachs - Bioengineering, 2019 - mdpi.com
The oviduct is the anatomical part of the female reproductive tract where the early
reproductive events take place, from gamete transport, fertilization and early embryo …
reproductive events take place, from gamete transport, fertilization and early embryo …