Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
[HTML][HTML] Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents
Gadolinium (III) complexes have been widely utilised as magnetic resonance imaging (MRI)
contrast agents for decades. In recent years however, concerns have developed about their …
contrast agents for decades. In recent years however, concerns have developed about their …
Lanthanide probes for bioresponsive imaging
The chemistry of the less familiar elements is a fascinating topic especially for the inorganic
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …
[图书][B] Handbook on the physics and chemistry of rare earths: including actinides
JCG Bunzli, VK Pecharsky - 2016 - books.google.com
Handbook on the Physics and Chemistry of Rare Earths: Including Actinides is a continuous
series of books covering all aspects of rare earth science, including chemistry, life sciences …
series of books covering all aspects of rare earth science, including chemistry, life sciences …
The use of the macrocyclic chelator DOTA in radiochemical separations
Radiometals play an important role in the diagnosis of physiological processes in vivo by
means of imaging technologies, but also increasingly contribute to the treatment of diseases …
means of imaging technologies, but also increasingly contribute to the treatment of diseases …
Rational Design of Gd-DOTA-Type Contrast Agents for Hepatobiliary Magnetic Resonance Imaging
W Xu, Y Lu, J Xu, H Li, R Lan, R Gao… - Journal of Medicinal …, 2023 - ACS Publications
The safety risks of gadolinium (Gd3+)-based contrast agents (GBCAs) arise from their
inevitable leakage of Gd3+, and the pursuit of more stable GBCAs for magnetic resonance …
inevitable leakage of Gd3+, and the pursuit of more stable GBCAs for magnetic resonance …
[HTML][HTML] Lanthanide complexes with polyaminopolycarboxylates as prospective NMR/MRI diagnostic probes: peculiarities of molecular structure, dynamics and …
EN Zapolotsky, Y Qu, SP Babailov - Journal of Inclusion Phenomena and …, 2022 - Springer
The paramagnetic lanthanide complexes with polyaminopolycarboxylate (PAPC) ligands
attract considerable attention from the standpoint of potential applications thereof as …
attract considerable attention from the standpoint of potential applications thereof as …
Structural Variations in Carboxylated Bispidine Ligands: Influence of Positional Isomerism and Rigidity on the Conformation, Stability, Inertness and Relaxivity of their …
Abstract Mn2+ complexes of 2, 4‐pyridyl‐disubstituted bispidine ligands have emerged as
more biocompatible alternatives to Gd3+‐based MRI probes. They display relaxivities …
more biocompatible alternatives to Gd3+‐based MRI probes. They display relaxivities …
[HTML][HTML] Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications
Despite established clinical utilisation, there is an increasing need for safer, more inert
gadolinium-based contrast agents, and for chelators that react rapidly with radiometals. Here …
gadolinium-based contrast agents, and for chelators that react rapidly with radiometals. Here …
Including and declaring structural fluctuations in the study of Lanthanide (III) coordination chemistry in solution
LG Nielsen, TJ Sørensen - Inorganic chemistry, 2019 - ACS Publications
The physicochemical properties of lanthanide (III) ions are directly linked to the structure of
the surrounding ligands. Rapid ligand exchange prohibits direct structure–property …
the surrounding ligands. Rapid ligand exchange prohibits direct structure–property …