The majority of blood cancers occur in the elderly. This fact conspires with an aging
population in many countries to make rigorous assessment for frailty increasingly important …

The frailty index (FI) quantifies frailty as deficit accumulation. It has been adapted to employ
laboratory test data (FI-Lab). Our objective was to systematically review and meta-analyse …

Purpose To provide guidance regarding the practical assessment and management of
vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was …

This study aimed to evaluate whether gait speed and grip strength predicted clinical
outcomes among older adults with blood cancers. We prospectively recruited 448 patients …

In 2023, ASCO updated its guideline on assessment and management of vulnerabilities in
older patients undergoing chemotherapy. The update revisited recommendations from the …

Purpose To determine treatment and aging-related effects on longitudinal cognitive function
in older breast cancer survivors. Methods Newly diagnosed nonmetastatic breast cancer …

Background: An objective measure is needed to identify frail older adults with cancer who
are at increased risk for poor health outcomes. The primary objective of this study was to …

Importance Although older patients are at increased risk of developing grade 3 or higher
chemotherapy-related toxic effects, no studies, to our knowledge, have focused on the …

Background Older adults with cancer are at increased risk of treatment‐related toxicities and
excess mortality. We evaluated whether a patient‐reported geriatric assessment (GA) based …

Importance The practice of oncology will increasingly involve the care of a growing
population of individuals with midlife and late-life cancers. Managing cancer in these …