Sterically demanding trialkylphosphines for palladium-catalyzed cross coupling reactions—alternatives to PtBu3

CA Fleckenstein, H Plenio - Chemical Society Reviews, 2010 - pubs.rsc.org
The strong electron-donation and the steric bulk of trialkylphosphines renders them as very
useful ligands for palladium-catalyzed cross coupling reactions. This critical review reports …

Highly efficient two-step synthesis of (Z)-2-halo-1-iodoalkenes from terminal alkynes

Z Chen, H Jiang, Y Li, C Qi - Chemical communications, 2010 - pubs.rsc.org
Highly efficient two-step synthesis of ( Z )-2-halo-1-iodoalkenes from terminal alkynes -
Chemical Communications (RSC Publishing) DOI:10.1039/C0CC02156C Royal Society of …

Highly E-selective solvent-free Horner–Wadsworth–Emmons reaction catalyzed by DBU

K Ando, K Yamada - Green Chemistry, 2011 - pubs.rsc.org
The solvent-free Horner–Wadsworth–Emmons reaction of triethyl phosphonoacetate with a
variety of aldehydes was catalyzed by DBU in the presence of K2CO3 to give E-α, β …

Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC‐33 Compounds: Promising Neuroprotective Agents Acting as σ1 …

D Rossi, A Pedrali, R Gaggeri, A Marra… - …, 2013 - Wiley Online Library
Our recent research efforts identified racemic RC‐33 as a potent and metabolically stable σ1
receptor agonist. Herein we describe the isolation of pure RC‐33 enantiomers by chiral …

Highly Regioselective and E/Z-Selective Hydroalkylation of Ynone, Ynoate, and Ynamide via Photoredox Mediated Ni/Ir Dual Catalysis

SY Go, GS Lee, SH Hong - Organic letters, 2018 - ACS Publications
Exclusively α-and highly E/Z-selective hydroalkylation of ynone, ynoate, and ynamide was
achieved via photoredox mediated Ni/Ir dual catalysis with high atom and step economy …

Palladium-Catalyzed Domino Reaction for Stereoselective Synthesis of Multisubstituted Olefins: Construction of Blue Luminogens

TT Hao, HR Liang, YH Ou-Yang, CZ Yin… - The Journal of …, 2018 - ACS Publications
The first Pd-catalyzed multicomponent reaction of aryl iodides, alkenyl bromides, and
strained alkenes has been developed, which allowed us to synthesize a variety of …

Enantioselective Synthesis of Di-and Tri-Arylated All-Carbon Quaternary Stereocenters via Copper-Catalyzed Allylic Arylations with Organolithium Compounds

S Guduguntla, JB Gualtierotti, SS Goh… - ACS Catalysis, 2016 - ACS Publications
The highly enantioselective copper (I)/N-heterocyclic carbene (NHC) catalyzed synthesis of
di-and triarylated all-carbon quaternary stereocenters via asymmetric allylic arylation (AAAr) …

Palladium-Catalyzed Modular Assembly of Electron-Rich Alkenes, Dienes, Trienes, and Enynes from (E)-1,2-Dichlorovinyl Phenyl Ether

LM Geary, PG Hultin - The Journal of Organic Chemistry, 2010 - ACS Publications
We have devised a modular construction of electron-rich alkene derivatives from
trichloroethylene (TCE). The three C− Cl bonds of TCE have sufficiently different reactivities …

Studies on the enantiomers of RC-33 as neuroprotective agents: Isolation, configurational assignment, and preliminary biological profile

D Rossi, A Pedrali, A Marra, L Pignataro… - Chirality, 2013 - Wiley Online Library
In this study we addressed the role of chirality in the biological activity of RC-33, recently
studied by us in its racemic form. An asymmetric synthesis procedure was the first …

Solvent-controlled retention or inversion of configuration in the Suzuki reaction of 2-bromo-1, 3-dienes: Stereodivergent synthesis of trisubstituted conjugated alkenes

RN Shakhmaev, MG Ignatishina, VV Zorin - Tetrahedron, 2022 - Elsevier
Abstract Suzuki coupling of 2-bromo-1, 3-dienes with various boronic acids proceeds with
retention or inversion of configuration of the Br-bearing double bond depending on the …