Bacterial nanotechnology as a paradigm in targeted cancer therapeutic delivery and immunotherapy

A Gholami, M Mohkam, S Soleimanian… - Microsystems & …, 2024 - nature.com
Cancer, a multifaceted and diverse ailment, presents formidable obstacles to traditional
treatment modalities. Nanotechnology presents novel prospects for surmounting these …

Encapsulated Bacteria with a Light-Repressed Deadman Switch for Liver Gene Delivery

M Renteln - 2024 - preprints.org
Adeno-associated viruses (AAVs) have been used for liver gene therapy. Hemgenix and
Roctavian are AAV-based treatments for hemophilia B and A, respectively. They cost $3 …

[PDF][PDF] Toward the Systemic Replacement of Mitochondrial DNA with Somatic Mutations

M Renteln - 2024 - preprints.org
The accumulation of lipofuscin, ie, indigestible intracellular debris, might be the main cause
of age-related diseases that we see today. However, without being able to replace mutated …

Ex Vivo Tissue-Resident Macrophage Replacement Prior to Allogeneic Transplantation

M Renteln - 2024 - preprints.org
Organ shortage is one of the most pressing issues with regard to human mortality. This issue
is further complicated by the fact that HLA matching is required for patients, leading to …