Masculinization depends on adequate production of testosterone by the fetal testis within a
specific “masculinization programming window.” Disorders resulting from subtle deficiencies …

Because of their wide range of actions on glucose homeostasis, lipid metabolism and
vascular inflammation, peroxisome proliferator-activated receptors (PPARs) are promising …

Peroxisome proliferator-activated receptors (PPARs) are ligand activated transcription
factors that modulate target gene expression in response to endogenous and exogenous …

At different stages of placental development the cytotrophoblasts differentiate into
specialized cells that are vital for specific placental tasks. These types include the invasive …

With the major attention to the pivotal roles of PPARs in diverse aspects of energy
metabolism, the essential functions of PPARγ and PPARβ/δ in placental development came …

OBJECTIVE: To prospectively assess whether metformin diet safely provides primary and
secondary prevention of gestational diabetes (GD). DESIGN: Assess development of GD on …

Peroxisome proliferator-activated receptor-gamma (PPAR-γ) belongs to the nuclear
hormone receptor superfamily. Apart from being involved in lipid metabolism, like its other …

Objective: To provide information on the use of oral antidiabetic agents in pregnancy and
breast-feeding. Data Sources: Primary articles were identified by a MEDLINE search (1966 …

Polycystic ovary syndrome (PCOS) is the most frequent cause of female infertility. The
treatment of PCOS patients with insulin sensitizers, such as metformin or thiazolidinediones …

Background: Insulin resistance and hyperinsulinemia may play a role in pathogenesis of
PCOS. One of the common therapeutic methods is using insulin-sensitizing drugs such as …