Apical–basal polarity and the control of epithelial form and function
CE Buckley, D St Johnston - Nature reviews Molecular cell biology, 2022 - nature.com
Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …
Programmed and self-organized flow of information during morphogenesis
C Collinet, T Lecuit - Nature Reviews Molecular Cell Biology, 2021 - nature.com
How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …
Adherens junctions as molecular regulators of emergent tissue mechanics
Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …
coordinated action of many cells. Recent studies have revealed that tissue material …
Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors
SJ Streichan, MF Lefebvre, N Noll, EF Wieschaus… - Elife, 2018 - elifesciences.org
During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding
into specific shapes. While developmental biology has identified key genes and local …
into specific shapes. While developmental biology has identified key genes and local …
Harnessing mechanobiology for tissue engineering
A primary challenge in tissue engineering is to recapitulate both the structural and functional
features of whole tissues and organs. In vivo, patterning of the body plan and constituent …
features of whole tissues and organs. In vivo, patterning of the body plan and constituent …
Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms
Evolutionary developmental biology, or Evo-Devo for short, has become an established field
that, broadly speaking, seeks to understand how changes in development drive major …
that, broadly speaking, seeks to understand how changes in development drive major …
[HTML][HTML] Self-organized nuclear positioning synchronizes the cell cycle in Drosophila embryos
VE Deneke, A Puliafito, D Krueger, AV Narla… - Cell, 2019 - cell.com
The synchronous cleavage divisions of early embryogenesis require coordination of the cell-
cycle oscillator, the dynamics of the cytoskeleton, and the cytoplasm. Yet, it remains unclear …
cycle oscillator, the dynamics of the cytoskeleton, and the cytoplasm. Yet, it remains unclear …
Rigidity transitions in development and disease
E Hannezo, CP Heisenberg - Trends in Cell Biology, 2022 - cell.com
Although rigidity and jamming transitions have been widely studied in physics and material
science, their importance in a number of biological processes, including embryo …
science, their importance in a number of biological processes, including embryo …
Principles and applications of optogenetics in developmental biology
D Krueger, E Izquierdo, R Viswanathan… - …, 2019 - journals.biologists.com
The development of multicellular organisms is controlled by highly dynamic molecular and
cellular processes organized in spatially restricted patterns. Recent advances in …
cellular processes organized in spatially restricted patterns. Recent advances in …
Signaling dynamics control cell fate in the early Drosophila embryo
HE Johnson, JE Toettcher - Developmental cell, 2019 - cell.com
The Erk mitogen-activated protein kinase plays diverse roles in animal development. Its
widespread reuse raises a conundrum: when a single kinase like Erk is activated, how does …
widespread reuse raises a conundrum: when a single kinase like Erk is activated, how does …