The dark side of the force–constraints and complications of cell therapies for stroke
Cell therapies are increasingly recognized as a promising option to augment the limited
therapeutic arsenal available to fight ischemic stroke. During the last two decades …
therapeutic arsenal available to fight ischemic stroke. During the last two decades …
Dental pulp stem cells: an attractive alternative for cell therapy in ischemic stroke
Ischemic stroke is a major cause of disability and mortality worldwide, but effective
restorative treatments are very limited at present. Regenerative medicine research revealed …
restorative treatments are very limited at present. Regenerative medicine research revealed …
A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …
on the responses of the neurovascular unit. Here, we report the development and …
Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial
Background Multipotent adult progenitor cells are a bone marrow-derived, allogeneic, cell
therapy product that modulates the immune system, and represents a promising therapy for …
therapy product that modulates the immune system, and represents a promising therapy for …
Adult neurogenesis in the subventricular zone and its regulation after ischemic stroke: implications for therapeutic approaches
Y Dillen, H Kemps, P Gervois, E Wolfs… - Translational stroke …, 2020 - Springer
Adult neurogenesis in the subventricular zone is a topic of intense research, since it has vast
implications for the fundamental understanding of the neurobiology of the brain and its …
implications for the fundamental understanding of the neurobiology of the brain and its …
Human muse cells reconstruct neuronal circuitry in subacute lacunar stroke model
H Uchida, K Niizuma, Y Kushida, S Wakao… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Multilineage-differentiating stress-enduring (muse) cells are
endogenous nontumorigenic stem cells with pluripotency harvestable as pluripotent marker …
endogenous nontumorigenic stem cells with pluripotency harvestable as pluripotent marker …
Behavioral outcome measures to improve experimental stroke research
Functional recovery after an experimental stroke can be assessed by multiple behavioral
tests, however, there is no consensus about which test to use in long-term stroke recovery …
tests, however, there is no consensus about which test to use in long-term stroke recovery …
Allogeneic adipose-derived mesenchymal stem cell sheet that produces neurological improvement with angiogenesis and neurogenesis in a rat stroke model
OBJECTIVE Stem cell therapy is a promising strategy for the treatment of severe cerebral
ischemia. However, targeting sufficient grafted cells to the affected area remains …
ischemia. However, targeting sufficient grafted cells to the affected area remains …
Stem cell transplantation for ischemic stroke
GB Boncoraglio, M Ranieri, A Bersano… - Cochrane Database …, 2019 - cochranelibrary.com
Background Stroke is a leading cause of morbidity and mortality worldwide, with very large
healthcare and social costs, and a strong demand for alternative therapeutic approaches …
healthcare and social costs, and a strong demand for alternative therapeutic approaches …
Parkinson's disease: from genetics and epigenetics to treatment, a miRNA-based strategy
E Paccosi, L Proietti-De-Santis - International Journal of Molecular …, 2023 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative disorders,
characterized by an initial and progressive loss of dopaminergic neurons of the substantia …
characterized by an initial and progressive loss of dopaminergic neurons of the substantia …