Volumetric muscle loss (VML) is a devastating loss of muscle tissue that overwhelms the
native regenerative properties of skeletal muscle and results in lifelong functional deficits …

The successful design of a hydrogel for tissue engineering requires a profound
understanding of its constituents' structural and molecular properties, as well as the proper …

Millions of Americans suffer from skeletal muscle injuries annually that can result in
volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss …

The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …

Volumetric muscle loss (VML), characterized by an irreversible loss of skeletal muscle due to
trauma or surgery, is accompanied by severe functional impairment and long-term disability …

Chondroitin sulfate (CS), a natural anionic mucopolysaccharide, belonging to the
glycosaminoglycan family, acts as the primary element of the extracellular matrix (ECM) of …

Recent years have witnessed significant progress in skeletal muscle tissue regeneration.
Numerous bioengineering approaches have been implemented to construct in vitro skeletal …

Tissue engineering strategies to treat patients with volumetric muscle loss (VML) aim to
recover the structure and contractile function of lost muscle tissue. Here, we assessed the …

Our goal was to understand the impact of regenerative therapies on the functional capacity
of skeletal muscle following volumetric muscle loss (VML) injury. An extensive database …

Adult skeletal muscle can regenerate effectively after mild physical or chemical insult.
Muscle trauma or disease can overwhelm this innate capacity for regeneration and result in …