Architecture, Function, Regulation, and Evolution of α-Glucans Metabolic Enzymes in Prokaryotes

JO Cifuente, C Colleoni, R Kalscheuer… - Chemical …, 2024 - ACS Publications
Bacteria have acquired sophisticated mechanisms for assembling and disassembling
polysaccharides of different chemistry. α-d-Glucose homopolysaccharides, so-called α …

[HTML][HTML] Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor

Y Huang, W Wurihan, B Lu, Y Zou, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living
bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of …

A chlamydial plasmid-dependent secretion system for the delivery of virulence factors to the host cytosol

L Lei, C Yang, MJ Patton, M Smelkinson, D Dorward… - Mbio, 2021 - Am Soc Microbiol
Chlamydia are obligate intracellular Gram-negative bacteria distinguished by a unique
developmental biology confined within a parasitophorous vacuole termed an inclusion. The …

Chlamydia trachomatis glycogen synthase promotes MAPK-mediated proinflammatory cytokine production via TLR2/TLR4 in THP-1 cells

Z Sun, Y Li, H Chen, L Xie, J Xiao, X Luan, B Peng, Z Li… - Life sciences, 2021 - Elsevier
Aims To investigate the roles and mechanisms of C. trachomatis glycogen synthase (GlgA)
in regulating the inflammatory response in THP-1 cells. Main methods In this work, after THP …

Expression profile screening and bioinformatics analysis of CircRNA, LncRNA, and mRNA in HeLa cells infected with Chlamydia muridarum

Y Liu, J Xiang, X Hu, H Wang, Y Sun - Archives of Microbiology, 2022 - Springer
We have previously shown that circRNAs in host cells are involved in the process of
Chlamydia trachomatis infection. In this study we aimed to identify significantly altered …

Can't live outside you: a thematic issue on obligate intracellular bacterial pathogens

J Coers, HJ Newton, JA Carlyon - Pathogens and Disease, 2021 - academic.oup.com
To establish their niches for microbial replication, obligate intracellular bacterial pathogens
co-opt numerous host cell resources and hijack metabolic pathways. Because of their …