Many functional RNAs have an evolutionarily conserved secondary structure. Conservation
of RNA base pairing induces pairwise covariations in sequence alignments. We developed …

The brucellae are facultative intracellular pathogens causing brucellosis, an important
zoonosis. Here, we review the nutritional, genetic, proteomic and transcriptomic studies on …

The symbiotic α-rhizobia Sinorhizobium meliloti, Bradyrhizobium japonicum, Rhizobium etli
and the related plant pathogen Agrobacterium tumefaciens are important model organisms …

Hfq is an RNA‐binding protein that functions in post‐transcriptional gene regulation by
mediating interactions between mRNAs and small regulatory RNAs (sRNAs). Two proteins …

The RNA chaperone Hfq is a global post-transcriptional regulator in bacteria. Here, we used
RNAseq to analyze RNA populations from the legume symbiont Sinorhizobium meliloti that …

Any method for RNA secondary structure prediction is determined by four ingredients. The
architecture is the choice of features implemented by the model (such as stacked basepairs …

Small noncoding RNAs (sRNAs) are ubiquitous posttranscriptional regulators of gene
expression. Using the model plant-pathogenic bacterium Xanthomonas campestris pv …

The legume symbiont Sinorhizobium meliloti expresses a plethora of small noncoding RNAs
(sRNAs) whose function is mostly unknown. Here, we have functionally characterized two …

Polyamines are ubiquitous molecules containing two or more amino groups that fulfill varied
and often essential physiological and regulatory roles in all organisms. In the symbiotic …

In any given organism, approximately one-third of all proteins have a yet-unknown function.
A widely distributed domain of unknown function is DUF1127. Approximately 17,000 …