Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …

In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …

Skeletal muscle is the largest organ determining whole‐body insulin sensitivity and
metabolic homoeostasis. Adaptive changes of skeletal muscle in response to physical …

Background Adolescence is a critical period for bone development, and peak bone mass
may be reached in late adolescence. Boosting bone accumulation at this time can help …

An imbalance between normal adipogenesis and osteogenesis by mesenchymal stem cells
(MSCs) has been shown to be related to various human metabolic diseases, such as obesity …

The effects of bariatric surgery on skeletal health are poorly understood. We found that
bariatric surgery patients are more prone to fracture when compared to the general …

During the last decades, obesity and osteoporosis have become important global health
problems, and the belief that obesity is protective against osteoporosis has recently come …

Obesity is one of the most serious worldwide epidemics of the twenty-first century according
to the World Health Organization. Frequently associated with a number of comorbidities …

Background: Obese individuals often present comorbidities while they appear protected
against the development of osteoporosis. However, few and contradictory data are now …

Bone mass can be viewed as the net product of two counteracting metabolic processes,
bone formation and bone resorption, which allow the skeleton to carry out its principal …