Approximately 15% of patients with prostate cancer are diagnosed with high-risk disease.
However, the current definitions of high-risk prostate cancer include a heterogeneous group …

Context The clinical significance of positive surgical margins (PSMs) in radical
prostatectomy (RP) specimens and the management of affected patients remain unclear …

Background Conventional imaging using CT and bone scan has insufficient sensitivity when
staging men with high-risk localised prostate cancer. We aimed to investigate whether novel …

Purpose: The summary presented herein covers recommendations on the early detection of
prostate cancer and provides a framework to facilitate clinical decision-making in the …

Background With the rapid development of technology, artificial intelligence (AI) has been
widely used in the diagnosis and prognosis prediction of a variety of diseases, including …

Purpose To assess long-term outcomes of men with favorable-risk prostate cancer in a
prospective, active-surveillance program. Methods Curative intervention was recommended …

Noninvasive, radiological image-based detection and stratification of Gleason patterns can
impact clinical outcomes, treatment selection, and the determination of disease status at …

Background Prostate tumor heterogeneity and biopsy undersampling pose challenges to
accurate, individualized risk assessment for men with localized disease. Objective To …

Background: Since primary prostate cancer (PCa) can advance to the life-threatening
metastatic PCa, exploring the molecular mechanisms underlying PCa metastasis is crucial …

Background Local failure after radical prostatectomy (RP) is common in patients with cancer
extending beyond the capsule. Three prospectively randomized trials demonstrated an …