Physical exercise (PE) improves physical performance, mental status, general health, and
well-being. It does so by affecting many mechanisms at the cellular and molecular level. PE …

This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

The beneficial effects of exercise on brain function have been demonstrated in animal
models and in a growing number of clinical studies on humans. There are multiple …

The rate of age-associated cognitive decline varies considerably between individuals. It is
important, both on a societal and individual level, to investigate factors that underlie these …

The neuroscience of exercise is a growing research area that is dedicated to furthering our
understanding of the effects that exercise has on mental health and athletic performance …

Major depressive disorder (MDD) is a prevalent psychiatric disorder associated with varied
prognosis, chronic course, and duration of illness with reduced quality of life. One factor that …

Exercise can enhance learning and memory and produce resistance against stress-related
psychiatric disorders such as depression and anxiety. In rats, these beneficial effects of …

Interest in space habitation has grown dramatically with planning underway for the first
human transit to Mars. Despite a robust history of domestic and international spaceflight …

Background: Shared connections between physical activity and neuroprotection have been
studied for decades, but the mechanisms underlying this effect of specific exercise were only …

Resilience is commonly conceptualized as the ability to adapt and thrive despite
experiencing adversity (Masten et al., 1995; Elder, 1998; Masten & Coatsworth, 1998). A …