▪ Abstract The synthesis of ribosomes is one of the major metabolic pathways in all cells. In
addition to around 75 individual ribosomal proteins and 4 ribosomal RNAs, synthesis of a …

The present review summarizes key progress made in characterizing the small nucleolar
RNAs (snoRNAs) of eukaryotic cells. Recent studies have shown snoRNA populations to be …

Nuclear ribonuclease (RNase) P is a ubiquitous essential ribonucleoprotein complex, one of
only two known RNA-based enzymes found in all three domains of life. The RNA component …

Ribosomes are perhaps the most critical macromolecular machine as they are tasked with
carrying out protein synthesis in cells. They are incredibly complex structures composed of …

Hal2p is an enzyme that converts pAp (adenosine 3′, 5′ bisphosphate), a product of
sulfate assimilation, into 5′ AMP and P i. Overexpression of Hal2p confers lithium …

Ribonuclease P (RNase P) is a ribonucleoprotein enzyme that cleaves precursor tRNA
transcripts to give mature 5′ ends. RNase P in eubacteria has a large, catalytic RNA …

The synthesis of ribosomes is one of the major cellular activities, and in eukaryotes, it takes
place primarily, although not exclusively, in a specialized subnuclear compartment termed …

The targets of in vivo studies of the ribosomal assembly process are mainly the events of
rRNA processing, whereas in vitro studies (total reconstitution) focus on principls of the …

RNA affinity tags would be very useful for the study of RNAs and ribonucleoproteins (RNPs)
as a means for rapid detection, immobilization, and purification. To develop a new affinity …

Proper regulation of ribosome biosynthesis is mandatory for cellular adaptation, growth and
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …