The microRNA-29 family: role in metabolism and metabolic disease

LT Dalgaard, AE Sørensen… - American Journal of …, 2022 - journals.physiology.org
The microRNA-29 family members miR-29a-3p, miR-29b-3p, and miR-29c-3p are
ubiquitously expressed and consistently increased in various tissues and cell types in …

miR-29a-3p/THBS2 axis regulates PAH-induced cardiac fibrosis

CH Hsu, IF Liu, HF Kuo, CY Li, WS Lian… - International journal of …, 2021 - mdpi.com
Pulmonary artery hypertension (PAH) pathology involves extracellular matrix (ECM)
remodeling in cardiac tissues, thus promoting cardiac fibrosis progression. miR-29a-3p …

miR-29b ameliorates atrial fibrosis in rats with atrial fibrillation by targeting TGFβRΙ and inhibiting the activation of Smad-2/3 pathway

X Han, S Wang, Z Yong, X Zhang, X Wang - Journal of Bioenergetics and …, 2022 - Springer
Objective Atrial fibrillation (AF) is a major cause of stroke with lifetime risks. microRNAs
(miRNAs) are associated with AF attenuation, yet the mechanism remains unknown. This …

Vaccine Formulation Strategies and Challenges Involved in RNA Delivery for Modulating Biomarkers of Cardiovascular Diseases: A Race from Laboratory to Market

MA Shaharyar, R Bhowmik, FA Al-Abbasi… - Vaccines, 2023 - mdpi.com
It has been demonstrated that noncoding RNAs have significant physiological and
pathological roles. Modulation of noncoding RNAs may offer therapeutic approaches as per …

Mare stromal endometrial cells differentially modulate inflammation depending on oestrus cycle status: an in vitro study

YS Wong, AC Mançanares, FI Navarrete… - Frontiers in Veterinary …, 2023 - frontiersin.org
The modulation of inflammation is pivotal for uterine homeostasis. Here we evaluated the
effect of the oestrus cycle on the expression of pro-inflammatory and anti-inflammatory …

竞争性内源性RNA 在创面愈合中作用的研究进展

廖银友, 张丕红 - 中华烧伤与创面修复杂志, 2022 - zhsszz.xml-journal.net
创面愈合作为重要的公共卫生问题之一, 一直是世界性难题. 由于独特的生物创面环境,
创面愈合是一个非常复杂的过程, 目前治疗周期长, 疗效欠佳, 患者经济负担重 …

An overview of CCN4 (WISP1) role in human diseases

K Singh, SS Oladipupo - Journal of Translational Medicine, 2024 - Springer
CCN4 (cellular communication network factor 4), a highly conserved, secreted cysteine-rich
matricellular protein is emerging as a key player in the development and progression of …

Differential DNA methylation landscape of miRNAs genes in mice liver fibrosis

D Li, W Yang, J Pang, G Yu - Molecular Biology Reports, 2024 - Springer
Background Patients with chronic liver disease were found nearly all to have liver fibrosis,
which is characterized by excess accumulation of extracellular matrix (ECM) proteins. While …

[HTML][HTML] Current Concepts in the Epigenetic Regulation of Cardiac Fibrosis

AF Hassanabad, AN Zarzycki, VB Patel… - Cardiovascular …, 2024 - Elsevier
Cardiac fibrosis is a significant driver of congestive heart failure, a syndrome that continues
to affect a growing patient population globally. Cardiac fibrosis results from a constellation of …

Therapeutic Acellular scaffolds for limiting left ventricular remodelling-current status and future directions

S Perveen, D Rossin, E Vitale, R Rosso… - International Journal of …, 2021 - mdpi.com
Myocardial infarction (MI) is one of the leading causes of heart-related deaths worldwide.
Following MI, the hypoxic microenvironment triggers apoptosis, disrupts the extracellular …